Recombinant Anti-EPHA3 Vesicular Antibody, EV Displayed (VS-0425-YC154)
CAT#: VS-0425-YC154
The Recombinant Anti-EPHA3 Vesicular Antibody, EV Displayed (VS-0425-YC154) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to EPHA3-expressed cells or tissues. The EPHA3 is an ephrin receptor involved in mediating developmental events, particularly in the nervous system.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm, plasma membrane, cytosol & actin filaments.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69390/1819_G10_18_cr59f32f9e0f828_selected.jpg
Normal Tissue
Figure 2 IHC staining of human parathyroid gland
Immunohistochemical staining of human parathyroid gland shows cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_B_9_5.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_A_8_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_A_9_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_A_5_6.jpg
Normal Tissue
Figure 7 Lymph node
Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enriched (AF22)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000044524-EPHA3
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- EPHA3
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- EPH receptor A3
- Biological Process
- Cell adhesion
- Molecular Function
- Kinase, Receptor, Transferase, Tyrosine-protein kinase
- Cellular Localization
- Nuclear membrane, Plasma membrane, Cytosol, Nucleoplasm, Actin filaments
- Introduction
- This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.
- Alternative Names
- ETK, ETK1, HEK, HEK4, TYRO4
- Gene ID
- 2042
- UniProt ID
- P29320
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC154. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "EPHA3"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-101LC | Recombinant Anti-Human EPHA3 Antibody (Fc glycosylation/Low fucosylated) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-101LC-1 | Recombinant Anti-Human EPHA3 Antibody (Fc glycosylation/Low fucosylated) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0651CT | Recombinant Mouse anti-Human EPHA3 Monoclonal antibody (EML056) | ICC, IF, WB | |
| HPAB-0007-LS | Human Anti-EPHA3 Recombinant Antibody (HPAB-0007-LS) | ELISA, FC | Human IgG κ |
| ZG-0294J | Mouse Anti-EPHA3 Recombinant Antibody (ZG-0294J) | WB, ELISA | Mouse IgG |
| VS3-XY630 | Mouse Anti-EPHA3 Recombinant Antibody (clone 6C1B6) | ELISA, WB | Mouse IgG2b |
| VS-0723-WK252 | Rabbit Anti-EPHA3 Recombinant Antibody (VS-0723-WK252) | ELISA, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1165 | Hi-Affi™ Rabbit Anti-EPHA3 Recombinant Antibody (clone DS1165AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-024ML | Anti-Human EPHA3 Recombinant Antibody (TAB-024ML) | ELISA, IHC, FC, IP, IF, FuncS | IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0007-LS-F(E) | Human Anti-EPHA3 Recombinant Antibody; Fab Fragment (HPAB-0007-LS-F(E)) | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0007-LS-S(P) | Human Anti-EPHA3 Recombinant Antibody; scFv Fragment (HPAB-0007-LS-S(P)) | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-024ML | Afuco™ Anti-EPHA3 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-024ML) | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| AFC-TAB-430CQ | Afuco™ Anti-EPHA3 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-430CQ) | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY104 | Human Anti-EPHA3 (clone KB004) scFv-Fc Chimera | ADCC | Human IgG1, scFv-Fc |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: Inhib, Cyt
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: WB, IHC, FC, Cyt, ELISA
Application: ELISA, SPR, Inhib, FuncS
Application: ELISA, FC, WB, FuncS
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, WB, Microarray, Block
Application: ELISA, FC, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
