Afuco™ Anti-EPHA3 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-024ML) (CAT#: AFC-TAB-024ML)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to EPHA3. It is a human monoclonal antibody that can be potentially used in the treatment of Myelodysplastic syndrome, Myelofibrosis, Cancer.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm, plasma membrane, cytosol & actin filaments.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69390/1819_G10_18_cr59f32f9e0f828_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm, plasma membrane, cytosol & actin filaments.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69390/1819_G10_18_cr59f32f9e0f828_selected.jpg
Figure 2 IHC staining of human parathyroid gland
(Immunohistochemical staining of human parathyroid gland shows cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/ihc_selected.jpg
(Immunohistochemical staining of human parathyroid gland shows cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/ihc_selected.jpg
Figure 3 Cerebral cortex
(Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_B_9_5.jpg
(Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_B_9_5.jpg
Figure 4 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_A_8_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_A_8_4.jpg
Figure 5 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_A_9_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_A_9_5.jpg
Figure 6 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_A_5_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_A_5_6.jpg
Figure 7 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_A_9_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_A_9_8.jpg
Figure 8 RNA cell line category: Cell line enriched (AF22)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000044524-EPHA3
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000044524-EPHA3
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Specificity
- Human EPHA3
- Species Reactivity
- Human
- Applications
- ELISA, IHC, FC, IP, IF, FuncS
- Conjugate
- Unconjugated
- Generic Name
- Fibatuzumab
- Related Disease
- Myelodysplastic syndrome, Myelofibrosis, Cancer
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Ephrin receptor A3; EPH receptor A3; ephrin type-A receptor 3; tyrosine protein kinase TYR04; tyrosine-protein kinase receptor REK4; ETK; ETK1; HEK; HEK4
- Gene ID
- 2042
- UniProt ID
- P29320
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "EPHA3"
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2640z | Mouse Anti-EPHA3 Recombinant Antibody (clone 18F1) | WB, ELISA | Mouse IgG2b |
| MOB-0651CT | Recombinant Mouse anti-Human EPHA3 Monoclonal antibody (EML056) | ICC/IF, WB | |
| ZG-0294J | Mouse Anti-EPHA3 Recombinant Antibody (ZG-0294J) | WB, ELISA | Mouse IgG |
| VS3-XY630 | Mouse Anti-EPHA3 Recombinant Antibody (clone 6C1B6) | ELISA, WB | Mouse IgG2b |
| VS-0723-WK252 | Rabbit Anti-EPHA3 Recombinant Antibody (VS-0723-WK252) | ELISA, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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