Afuco™ Anti-EPHA3 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-024ML) (CAT#: AFC-TAB-024ML)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to EPHA3. It is a human monoclonal antibody that can be potentially used in the treatment of Myelodysplastic syndrome, Myelofibrosis, Cancer.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm, plasma membrane, cytosol & actin filaments.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69390/1819_G10_18_cr59f32f9e0f828_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm, plasma membrane, cytosol & actin filaments.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69390/1819_G10_18_cr59f32f9e0f828_selected.jpg
Figure 2 IHC staining of human parathyroid gland
(Immunohistochemical staining of human parathyroid gland shows cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/ihc_selected.jpg
(Immunohistochemical staining of human parathyroid gland shows cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/ihc_selected.jpg
Figure 3 Cerebral cortex
(Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_B_9_5.jpg
(Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_B_9_5.jpg
Figure 4 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_A_8_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_A_8_4.jpg
Figure 5 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_A_9_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_A_9_5.jpg
Figure 6 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_A_5_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_A_5_6.jpg
Figure 7 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_A_9_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10462/24404_A_9_8.jpg
Figure 8 RNA cell line category: Cell line enriched (AF22)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000044524-EPHA3
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000044524-EPHA3
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Specificity
- Human EPHA3
- Species Reactivity
- Human
- Applications
- ELISA, IHC, FC, IP, IF, FuncS
- Conjugate
- Unconjugated
- Generic Name
- Fibatuzumab
- Related Disease
- Myelodysplastic syndrome, Myelofibrosis, Cancer
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Ephrin receptor A3; EPH receptor A3; ephrin type-A receptor 3; tyrosine protein kinase TYR04; tyrosine-protein kinase receptor REK4; ETK; ETK1; HEK; HEK4
- Gene ID
- 2042
- UniProt ID
- P29320
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "EPHA3"
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Please select product type
IgG Antibodies
Fc Glycosylation Antibodies
Low- or Non-fucosylated Oligosaccharide Antibodies
Rabbit Monoclonal Antibodies
Humanized Antibodies
ScFv Antibodies
Fab Antibodies
ADCC Enhanced Antibodies
ScFv-Fc Chimeras
Extracellular Vesicle Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2640z | Mouse Anti-EPHA3 Recombinant Antibody (clone 18F1) | WB, ELISA | Mouse IgG2b |
| HPAB-0007-LS | Human Anti-EPHA3 Recombinant Antibody (HPAB-0007-LS) | ELISA, FC | Human IgG κ |
| ZG-0294J | Mouse Anti-EPHA3 Recombinant Antibody (ZG-0294J) | WB, ELISA | Mouse IgG |
| VS3-XY630 | Mouse Anti-EPHA3 Recombinant Antibody (clone 6C1B6) | ELISA, WB | Mouse IgG2b |
| VS-0723-WK252 | Rabbit Anti-EPHA3 Recombinant Antibody (VS-0723-WK252) | ELISA, FC | Rabbit IgG |
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