Recombinant Anti-FGFR4 Vesicular Antibody, EV Displayed (VS-0425-YC308)

Name: Recombinant Anti-FGFR4 Vesicular Antibody, EV Displayed (VS-0425-YC308)
SKU: VS-0425-YC308
Rating: 5 (1 reviews)

CAT#: VS-0425-YC308

The Recombinant Anti-FGFR4 Vesicular Antibody, EV Displayed (VS-0425-YC308) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to FGFR4-expressed cells or tissues. The FGFR4 is a tyrosine kinase receptor that is crucial for various regulatory functions, including cell differentiation and metabolism, affecting mitogenesis through FGFs.

Gene Expression

Normal Tissue Figure 1 IHC staining of human smooth muscle

Immunohistochemical staining of human smooth muscle shows strong cytoplasmic positivity in smooth muscle cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27273/ihc_selected.jpg

Normal Tissue Figure 2 IHC staining of human gall bladder

Immunohistochemical staining of human gall bladder shows strong cytoplasmic and membrane positivity in glandular cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/ihc_selected.jpg

Normal Tissue Figure 3 IHC staining of human prostate

Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5196/ihc_selected.jpg

Normal Tissue Figure 4 Colon

Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_9_3.jpg

Normal Tissue Figure 5 Liver

Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_9_4.jpg

Normal Tissue Figure 6 Kidney

Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_7_5.jpg

Normal Tissue Figure 7 Testis

Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_4_6.jpg

RNA Expression Figure 8 RNA cell line category: Group enriched (CACO-2, Hep G2, RH-30)

Cell lines ordered by descending RNA expression order

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000160867-FGFR4

❮

❯

Recombinant Antibody

Application
ELISA, FC, Inhib, Cell-uptake

Product Type
Ab-Fc-EVs

Antibody Quantification (Ab/EV)
~100 Ab/EV

Target
FGFR4

Host Animal
Rat

Antibody Isotype
IgG

Species Reactivity
Human

Expression Cell
Mammalian cell

Engineered EVs

EV-sorting domain
CD63

Fc-binding domain
Protein A

EV Size
30~150 nm

Producing Cell
HEK293F

Isolation Method
Gradient centrifugation

Purification
qEV size exclusion chromatography

Concentration
1 x 10¹⁰

Size
1 mL

Buffer
PBS

Storage
Store at -80°C for 12 months

Target

Full Name
Fibroblast growth factor receptor 4

Molecular Function
Kinase, Receptor, Transferase, Tyrosine-protein kinase

Introduction
The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.

Alternative Names
CD334, JTK2

Gene ID
2264

UniProt ID
P22455

REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS

Inquiry

Navs

Customer Review

There are currently no Customer reviews or questions for VS-0425-YC308. Click the button above to contact us or submit your feedback about this product.

Submit Your Publication

Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

Related Diseases

EGFR Tyrosine Kinase Inhibitor Resistance

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Datasheet

Datasheet - VS-0425-YC308.pdf

MSDS

MSDS - VS-0425-YC308.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

See other products for "FGFR4"

Select a product category from the dropdown menu below to view related products.

CAT	Product Name	Application	Type
MOB-3383z	Mouse Anti-FGFR4 Recombinant Antibody (clone 31F7)	WB, IP, IF, IHC, ELISA	Mouse IgG1, κ
MOB-0739CT	Recombinant Mouse anti-Human FGFR4 Monoclonal antibody (NN0390-7I44)	WB
HPAB-0054-LS	Human Anti-FGFR4 Recombinant Antibody (HPAB-0054-LS)	Inhib	Human IgG
HPAB-0055-LS	Human Anti-FGFR4 Recombinant Antibody (HPAB-0055-LS)	Inhib	Human IgG
VS-0723-WK114	Human Anti-FGFR4 Recombinant Antibody (VS-0723-WK114)	FC	Chimeric (rabbit/human) IgG1

CAT	Product Name	Application	Type
TAB-066WM	Anti-Human FGFR4 Recombinant Antibody (XPA.48.056)	ELISA, FC	Human Antibody
TAB-066WM-F(E)	Anti-Human FGFR4 Recombinant Antibody Fab Fragment (XPA.48.056)	ELISA, FC	Human Antibody
TAB-384CQ	Human Anti-FGFR4 Recombinant Antibody (TAB-384CQ)	ELISA	Human IgG
TAB-384CQ-S(P)	Human Anti-FGFR4 Recombinant Antibody; scFv Fragment (TAB-384CQ-S(P))	ELISA	Human scFv
TAB-384CQ-F(E)	Human Anti-FGFR4 Recombinant Antibody; Fab Fragment (TAB-384CQ-F(E))	ELISA	Human Fab

CAT	Product Name	Application	Type
TAB-067WM	Anti-Human FGFR4 Recombinant Antibody (F85-6C5)	IP, ELISA
TAB-068WM	Mouse Anti-FGFR4 Recombinant Antibody (TAB-068WM)	ELISA, WB	Mouse IgG
TAB-069WM	Rat Anti-FGFR4 Recombinant Antibody (TAB-069WM)	ELISA, WB, FC, Inhib	Rat IgG
TAB-065WM-F(E)	Mouse Anti-FGFR4 Recombinant Antibody; Fab Fragment (TAB-065WM-F(E))	ELISA, FC	Mouse Fab
TAB-067WM-F(E)	Anti-Human FGFR4 Recombinant Antibody Fab Fragment (F85-6C5)	ELISA

CAT	Product Name	Application	Type
MOR-1300	Hi-Affi™ Rabbit Anti-FGFR4 Recombinant Antibody (clone DS1300AB)	WB	Rabbit IgG
MOR-4575	Hi-Affi™ Rabbit Anti-FGFR4 Recombinant Antibody (clone TH87DS)	WB	Rabbit IgG

CAT	Product Name	Application	Type
HPAB-0054-LS-S(P)	Human Anti-FGFR4 Recombinant Antibody; scFv Fragment (HPAB-0054-LS-S(P))	Inhib	Human scFv
HPAB-0055-LS-S(P)	Human Anti-FGFR4 Recombinant Antibody; scFv Fragment (HPAB-0055-LS-S(P))	Inhib	Human scFv
HPAB-0056-LS-S(P)	Human Anti-FGFR4 Recombinant Antibody; scFv Fragment (HPAB-0056-LS-S(P))	Inhib	Human scFv
HPAB-2922LY-S(P)	Mouse Anti-FGFR4 Recombinant Antibody; scFv Fragment (HPAB-2922LY-S(P))	ELISA, FC	Mouse scFv
HPAB-0442-FY-S(P)	Human Anti-FGFR4 Recombinant Antibody; scFv Fragment (HPAB-0442-FY-S(P))	Inhib	Human scFv

CAT	Product Name	Application	Type
HPAB-0054-LS-F(E)	Human Anti-FGFR4 Recombinant Antibody; Fab Fragment (HPAB-0054-LS-F(E))	Inhib	Human Fab
HPAB-0055-LS-F(E)	Human Anti-FGFR4 Recombinant Antibody; Fab Fragment (HPAB-0055-LS-F(E))	Inhib	Human Fab
HPAB-0056-LS-F(E)	Human Anti-FGFR4 Recombinant Antibody; Fab Fragment (HPAB-0056-LS-F(E))	Inhib	Human Fab
HPAB-2922LY-F(E)	Mouse Anti-FGFR4 Recombinant Antibody; Fab Fragment (HPAB-2922LY-F(E))	ELISA, FC	Mouse Fab
HPAB-0442-FY-F(E)	Human Anti-FGFR4 Recombinant Antibody; Fab Fragment (HPAB-0442-FY-F(E))	Inhib	Human Fab

CAT	Product Name	Application	Type
NS-028CN	Mouse Anti-FGFR4 Recombinant Antibody (clone LD1)	ELISA, WB, FC, IHC, IP	Mouse IgG1
NS-028CN-F(E)	Mouse Anti-FGFR4 Recombinant Antibody (clone LD1); Fab Fragment	ELISA, WB, FC, IHC, IP	Mouse Fab
NS-028CN-S(P)	Mouse Anti-FGFR4 Recombinant Antibody (clone LD1); scFv Fragment	ELISA, WB, FC, IHC, IP	Mouse scFv

CAT	Product Name	Application	Type
MHC-YF433	A*02:01/Human FGFR4 (ALLAGLVSL) MHC Pentamer	FCM

CAT	Product Name	Application	Type
VS-0424-XY103	AbPlus™ Anti-FGFR4 Magnetic Beads (F85-6C5)	IP, Protein Purification

CAT	Product Name	Application	Type
VS-0525-XY2545	Anti-FGFR4 Immunohistochemistry Kit	IHC

Specific Inquiry

Add to compare

See Our Custom Production in Action

Figure 1 Anti-HBV Recombinant Antibody (TAB-147) in SDS-PAGE

Download the full case study

Popular Products

Figure 4 Mouse Anti-ACTA2 Antibody (ZG-1036F) in IHC

Mouse Anti-ACTA2 Recombinant Antibody (clone HHF35) (CAT# ZG-1036F)
Application: EM, ELISA, ICC, IHC-Fr, IHC-P, WB

Figure 2 Mouse Anti-Anti-HIV-1 antibody VRC01 Anti-idiotype Antibody (PABJ-0191) in HPLC

Mouse Anti-Anti-HIV-1 antibody VRC01 Anti-idiotype Antibody (clone iv8) (CAT# PABJ-0191)
Application: ELISA, Vaccine, FuncS

Figure 4 Human Anti-PEG Recombinant Antibody (FAMAB-1525CQ) in ELISA

Human Anti-PEG Recombinant Antibody (clone E11) (CAT# FAMAB-1525CQ)
Application: WB, ELISA, FC

Figure 3 Mouse Anti-IL17RB Recombinant Antibody (HPAB-AP684-YC) in ELISA

Mouse Anti-IL17RB Recombinant Antibody (HPAB-AP684-YC) (CAT# HPAB-AP684-YC)
Application: Neut, FuncS, IHC, ELISA, FC, Inhib

Figure 2 Mouse Anti-CRP Recombinant Antibody; Fab Fragment (HPAB-M0039-YC-F(E)) in ELISA

Mouse Anti-CRP Recombinant Antibody (clone P24); Fab Fragment (CAT# HPAB-M0039-YC-F(E))
Application: ELISA

Figure 1 Anti-HBV Recombinant Antibody (TAB-147) in SDS-PAGE

Anti-HBV Recombinant Antibody (TAB-147) (CAT# TAB-147)
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC

Figure 4 Anti-Human PCSK9 Recombinant Antibody (TAB-H31) in HPLC

Human Anti-PCSK9 Recombinant Antibody (TAB-H31) (CAT# TAB-H31)
Application: FC, IP, ELISA, Neut, FuncS, IF, IHC

Figure 2 Anti-Human MUC5AC Recombinant Antibody (TAB-200) in SEC-HPLC

Anti-Human MUC5AC Recombinant Antibody (TAB-200) (CAT# TAB-200)
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC

Figure 2 Anti-Human SLC34A2 Antibody (TAB-H45) in HPLC

Human Anti-SLC34A2 Recombinant Antibody (TAB-H45) (CAT# TAB-H45)
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC

Figure 4 Human Anti-HIV-1 gp41 Recombinant Antibody (clone 2F5) (PABL-186) in DB

Human Anti-HIV-1 gp41 Recombinant Antibody (clone 2F5) (CAT# PABL-186)
Application: WB, Neut, FuncS

Figure 10 Recombinant Human Anti-RSV Antibody, HRP (PABL-322-HRP) in Absorption Spectroanalysis

Recombinant Human Anti-RSV Antibody (D25) (CAT# PABL-322)
Application: WB, ELISA, Neut, FuncS

Figure 5 Recombinant Mouse Anti-DENV-3 Antibody (PABL-446) in HPLC

Recombinant Mouse Anti-DENV-3 Antibody (mAb 4E11) (CAT# PABL-446)
Application: WB, FuncS

Figure 2 Anti-Human CD19 Recombinant Antibody Fab Fragment [TAB-1611CL-F(E)] in HPLC

Mouse Anti-CD19 Recombinant Antibody; Fab Fragment (TAB-1611CL-F(E)) (CAT# TAB-1611CL-F(E))
Application: Depletion, FuncS

Figure 6 Anti-Human CD28 Recombinant Antibody (TAB-064LC), Fc Silenced, in ELISA

Anti-Human CD28 Recombinant Antibody (TGN1412) (CAT# TAB-064LC)
Application: FC, Stim

Figure 5 Mouse Anti-HAVCR1 Recombinant Antibody (TAB-664CT) in DB

Mouse Anti-HAVCR1 Recombinant Antibody (TAB-664CT) (CAT# TAB-664CT)
Application: FC, IB, Block, Inhib, FuncS, ELISA, FACS, IP, IF

Figure 4 Mouse Anti-MUC1 Recombinant Antibody (5E5) (TAB-418MZ) in HPLC

Mouse Anti-MUC1 Recombinant Antibody (TAB-418MZ) (CAT# TAB-418MZ)
Application: ELISA, FuncS, IHC, IF, FC, ADCC

Figure 3 Anti-Human SELP Recombinant Antibody (TAB-015ML) in HPLC

Anti-Human SELP Recombinant Antibody (TAB-015ML) (CAT# TAB-015ML)
Application: ELISA, IHC, FC, IP, IF, FuncS

Figure 3 Anti-CD40 Antibody in (MOB-120CQ) Dot Blot

Human Anti-CD40 Recombinant Antibody (MOB-120CQ) (CAT# MOB-120CQ)
Application: ELISA, IHC, IF, IP, FC, FuncS

Figure 14 Human Anti-IAV HA Antibody (PABC-393) in DB 4

Recombinant Human Anti-IAV HA Antibody (PABC-393) (CAT# PABC-393)
Application: Neut, FuncS, ELISA

Figure 7 Human Anti-IAV HA Recombinant Antibody (HPAB-M0100-YC) in DB

Human Anti-HA Recombinant Antibody (HPAB-M0100-YC) (CAT# HPAB-M0100-YC)
Application: ELISA, FuncS