Recombinant Anti-FLT1 Vesicular Antibody, EV Displayed (VS-0425-YC224)
CAT#: VS-0425-YC224
The Recombinant Anti-FLT1 Vesicular Antibody, EV Displayed (VS-0425-YC224) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to FLT1-expressed cells or tissues. The FLT1 is a vascular endothelial growth factor receptor, involved in angiogenesis. Multiple isoforms include soluble forms associated with pre-eclampsia.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11740/90_G3_2_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line BJ
Immunofluorescent staining of human cell line BJ shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11740/1368_A5_2_blue_green.jpg
Normal Tissue
Figure 3 Testis
Peritubular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Sertoli cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11740/142518_A_6_6.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, HMC-1, HUVEC TERT2, WM-115)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000102755-FLT1
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- FLT1
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Fms related receptor tyrosine kinase 1
- Biological Process
- Angiogenesis, Chemotaxis, Differentiation
- Molecular Function
- Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase
- Cellular Localization
- Plasma membrane, Actin filaments, Cytosol
- Introduction
- This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]
- Alternative Names
- FLT, VEGFR1
- Gene ID
- 2321
- UniProt ID
- P17948
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Related Diseases
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
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| TAB-008CQ | Mouse Anti-FLT1 Recombinant Antibody (TAB-008CQ) | ELISA, FC | Mouse IgG |
| TAB-008CQ-S(P) | Mouse Anti-FLT1 Recombinant Antibody; scFv Fragment (TAB-008CQ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-008CQ-F(E) | Mouse Anti-FLT1 Recombinant Antibody; Fab Fragment (TAB-008CQ-F(E)) | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-009CQ | Human Anti-FLT1 Recombinant Antibody (TAB-009CQ) | ELISA | Chimeric antibody (mouse/human) |
| TAB-009CQ-S(P) | Mouse Anti-FLT1 Recombinant Antibody; scFv Fragment (TAB-009CQ-S(P)) | ELISA | Mouse scFv |
| TAB-009CQ-F(E) | Human Anti-FLT1 Recombinant Antibody; Fab Fragment (TAB-009CQ-F(E)) | ELISA | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-845CQ | Mouse Anti-FLT1 Recombinant Antibody (clone MAB0702) | WB, Block | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1322 | Hi-Affi™ Rabbit Anti-FLT1 Recombinant Antibody (clone DS1322AB) | WB, IHC-P, ICC, IF, IP, ELISA, IHC-P, IHC-Fr | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0785-CN | Mouse Anti-FLT1 Recombinant Antibody (clone 1-833-527) | ELISA, FC | Mouse IgG, κ |
| MRO-2272-CN | Rabbit Anti-FLT1 Polyclonal Antibody (MRO-2272-CN) | WB, IHC | Rabbit IgG |
| HPAB-M0695-YC | Mouse Anti-FLT1 Recombinant Antibody (HPAB-M0695-YC) | ELISA, WB, FuncS | Mouse IgG1 |
| HPAB-0499-YJ | Human Anti-FLT1 Recombinant Antibody (HPAB-0499-YJ) | ELISA, Block, FuncS | Human IgG1 |
| VS3-XY713 | Mouse Anti-FLT1 Recombinant Antibody (clone 3D10) | ELISA, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0785-CN-F(E) | Mouse Anti-FLT1 Recombinant Antibody (clone 1-833-527); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0065-YJ-F(E) | Mouse Anti-FLT1 Recombinant Antibody (clone 6.12); Fab Fragment | Inhib | Mouse Fab |
| HPAB-0499-YJ-F(E) | Human Anti-FLT1 Recombinant Antibody; Fab Fragment (HPAB-0499-YJ-F(E)) | ELISA, Block, FuncS | Human Fab |
| HPAB-0500-YJ-F(E) | Human Anti-FLT1 Recombinant Antibody; Fab Fragment (HPAB-0500-YJ-F(E)) | ELISA, Block, FuncS | Human Fab |
| HPAB-0501-YJ-F(E) | Mouse Anti-FLT1 Recombinant Antibody; Fab Fragment (HPAB-0501-YJ-F(E)) | ELISA, Block, FuncS | Chimeric (mouse/rat) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1606LY-S(P) | Human Anti-FLT1 Recombinant Antibody; scFv Fragment (HPAB-1606LY-S(P)) | ELISA | Human scFv |
| HPAB-1607LY-S(P) | Human Anti-FLT1 Recombinant Antibody; scFv Fragment (HPAB-1607LY-S(P)) | ELISA | Human scFv |
| HPAB-1609LY-S(P) | Human Anti-FLT1 Recombinant Antibody; scFv Fragment (HPAB-1609LY-S(P)) | ELISA | Human scFv |
| HPAB-1610LY-S(P) | Human Anti-FLT1 Recombinant Antibody; scFv Fragment (HPAB-1610LY-S(P)) | ELISA | Human scFv |
| HPAB-1611LY-S(P) | Human Anti-FLT1 Recombinant Antibody; scFv Fragment (HPAB-1611LY-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-177 | Afuco™ Anti-FLT1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-177) | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0673 | PE-A*02:01/Human FLT1 (TLFWLLTL) MHC Tetramer | FCM, IHC | |
| MHC-CN0674 | APC-A*02:01/Human FLT1 (TLFWLLTL) MHC Tetramer | FCM, IHC | |
| MHC-CN0675 | FITC-A*02:01/Human FLT1 (TLFWLLTL) MHC Tetramer | FCM, IHC | |
| MHC-CN0676 | A*02:01/Human FLT1 (TLFWLLTL) MHC Tetramer | FCM, IHC | |
| MHC-CN1412 | PE-A*24:02/Human FLT1 (SYGVLLWEI) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY850 | Anti-FLT1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2581 | Anti-Mouse FLT1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2582 | Anti-Zebrafish FLT1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2580 | Anti-Human FLT1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY53 | Mouse Anti-FLT1 scFv-Fc Chimera (VS-0425-FY53) | WB, ELISA, Inhib | Mouse IgG1, scFv-Fc |
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