Recombinant Anti-IFNAR1 Vesicular Antibody, EV Displayed (VS-0425-YC253) (CAT#: VS-0425-YC253)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• IFNAR1

• Host Animal
• Human

• Antibody Isotype
• IgG4 kappa

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 1.84 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Interferon alpha and beta receptor subunit 1

• Molecular Function
• Receptor

• Introduction
• The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.

• Alternative Names
• IFNAR, IFRC

• Gene ID
• 3454

• UniProt ID
• P17181

Select a product category from the dropdown menu below to view related products.