Recombinant Anti-IFNAR1 Vesicular Antibody, EV Displayed (VS-0425-YC253)
CAT#: VS-0425-YC253
The Recombinant Anti-IFNAR1 Vesicular Antibody, EV Displayed (VS-0425-YC253) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to IFNAR1-expressed cells or tissues. The IFNAR1 is a membrane protein forming part of the receptor for type I interferons, participating in antiviral processes.
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- IFNAR1
- Host Animal
- Human
- Antibody Isotype
- IgG4 kappa
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 1.84 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Interferon alpha and beta receptor subunit 1
- Molecular Function
- Receptor
- Introduction
- The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.
- Alternative Names
- IFNAR, IFRC
- Gene ID
- 3454
- UniProt ID
- P17181
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Datasheet
MSDS
COA
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