Recombinant Anti-IFNAR1 Vesicular Antibody, EV Displayed (VS-0425-YC253)
CAT#: VS-0425-YC253
The Recombinant Anti-IFNAR1 Vesicular Antibody, EV Displayed (VS-0425-YC253) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to IFNAR1-expressed cells or tissues. The IFNAR1 is a membrane protein forming part of the receptor for type I interferons, participating in antiviral processes.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29226/75714_B_9_5.jpg
Normal Tissue
Figure 2 Testis
Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29226/75714_A_4_6.jpg
Normal Tissue
Figure 3 Lymph node
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29226/75714_A_9_8.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (Karpas-707)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142166-IFNAR1
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- IFNAR1
- Host Animal
- Human
- Antibody Isotype
- IgG4 kappa
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 1.84 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Interferon alpha and beta receptor subunit 1
- Molecular Function
- Receptor
- Introduction
- The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.
- Alternative Names
- IFNAR, IFRC
- Gene ID
- 3454
- UniProt ID
- P17181
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Datasheet
MSDS
COA
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1305z-S(P) | Recombinant Anti-Human IFNAR1 Antibody scFv Fragment | RIA, ELISA, FuncS | scFv |
| HPAB-0203CQ-S(P) | Human Anti-IFNAR1 Recombinant Antibody (clone H3K1); scFv Fragment | ELISA, FC, Inhib | Humanized scFv |
| HPAB-0204CQ-S(P) | Human Anti-IFNAR1 Recombinant Antibody; scFv Fragment (HPAB-0204CQ-S(P)) | ELISA, WB, FC, Inhib | Human scFv |
| HPAB-0205CQ-S(P) | Human Anti-IFNAR1 Recombinant Antibody; scFv Fragment (HPAB-0205CQ-S(P)) | ELISA, WB, FC, Inhib | Human scFv |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-130CT | Anti-Human IFNAR-1 Recombinant Antibody (64G12) | WB, IF, FuncS | |
| TAB-130CT-S(P) | Anti-Human IFNAR-1 Recombinant Antibody scFv Fragment (64G12) | ELISA, FC | |
| TAB-130CT-F(E) | Anti-Human IFNAR-1 Recombinant Antibody Fab Fragment (64G12) | ELISA, FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-131CT | Anti-Human IFNAR-1 Recombinant Antibody (CPI-1697) | ELISA, FC | Humanized antibody |
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| TAB-131CT-F(E) | Anti-Human IFNAR-1 Recombinant Antibody Fab Fragment (CPI-1697) | ELISA, FC | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1740 | Rabbit Anti-IFNAR1 Recombinant Antibody (clone DS1740AB) | WB, FC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-722 | Afuco™ Anti-IFNAR ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-722) | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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