Afuco™ Anti-IFNAR ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-722) (CAT#: AFC-TAB-722)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant human monoclonal antibody expressed in CHO binding to human interferon α/β receptor. It is a monoclonal antibody designed for the treatment of systemic lupus erythematosus.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29226/75714_B_9_5.jpg
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29226/75714_B_9_5.jpg
Figure 2 Testis
(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29226/75714_A_4_6.jpg
(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29226/75714_A_4_6.jpg
Figure 3 Lymph node
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29226/75714_A_9_8.jpg
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29226/75714_A_9_8.jpg
Figure 4 RNA cell line category: Cell line enhanced (Karpas-707)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142166-IFNAR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142166-IFNAR1
Figure 4 RNA cell line category: Cell line enhanced (Karpas-707)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142166-IFNAR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142166-IFNAR1
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- FuncS, IF, Neut, ELISA, FC, IP
- Conjugate
- Unconjugated
- Generic Name
- Anifrolumab
- Related Disease
- Diffuse scleroderma
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- interferon-α/β receptor; IFNAR
Related Resources
Please refer to Anifrolumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Anifrolumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Anifrolumab"
DrugMonitor™ Anti-Anifrolumab Antibody (VS-1224-YC89)Anifrolumab is an IgG1 kappa monoclonal antibody that inhibits the type 1 interferon receptor (IFNAR), indicated for adults with moderate to severe systemic lupus erythematosus. The DrugMonitor™ Anti-Anifrolumab Antibody (VS-1224-YC89) is an anti-drug antibody (ADA) against Anifrolumab. This drug-based antibody is raised in mice immunized with the Anifrolumab. The anti-Anifrolumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Anifrolumab in samples.
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-228 | Human Anti-IFNAR1 Recombinant Antibody (clone MEDI546) | WB, ELISA, FuncS | Human IgG |
| HPAB-0203CQ | Human Anti-IFNAR1 Recombinant Antibody (clone H3K1) | ELISA, FC, Inhib | Humanized IgG1 |
| HPAB-0204CQ | Human Anti-IFNAR1 Recombinant Antibody (HPAB-0204CQ) | ELISA, WB, FC, Inhib, FuncS | Human IgG1 |
| VS3-FY727 | Recombinant Mouse Anti-IFNAR1 Antibody (clone 2A5B12) | ELISA, WB, IHC, FC | Mouse IgG1 |
| VS3-FY728 | Recombinant Rabbit Anti-IFNAR1 Antibody (clone R09-7D6) | WB, IP | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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