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    Human Anti-IFNAR1 Recombinant Antibody (clone S5B4) (CAT#: HPAB-0159-CN)

    Antibody S5B4 is a novel human antibody that specifically binds to human IFNAR1, which can inhibit the type I interferon-mediated cell signaling pathway.

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Published Data
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    FC

    Figure 1 IFNAR blockade during cART reduces cART-resistant HIV-1 reservoirs.

    Figure 1 IFNAR blockade during cART reduces cART-resistant HIV-1 reservoirs.

    Hu-mice infected with HIV-1 were treated with cART from 4 to 12 wpi. From 7 to 10 wpi, the cART-treated mice were injected with α-IFNAR1 antibody or isotype control mIgG2a antibody.

    Cheng, L., Ma, J., Li, J., Li, D., Li, G., Li, F., ... & Tsao, L. C. (2017). Blocking type I interferon signaling enhances T cell recovery and reduces HIV-1 reservoirs. The Journal of clinical investigation, 127(1), 269-279.


    Specifications

    • Immunogen
    • Recombinant hIFNARl-his
    • Host Species
    • Human
    • Type
    • Human IgG
    • Specificity
    • Human IFNAR1
    • Species Reactivity
    • Human
    • Clone
    • S5B4
    • Applications
    • FC
    • Related Disease
    • Cancer

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE and HPLC analysis
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Preservative
    • No preservatives
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Applications

    • Application Notes
    • The IFNAR1 antibody has been reported in applications of Flow Cytometry.

    Target

    • Alternative Names
    • AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "Clone S5B4"

    See other products for "IFNAR1"

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    Please select product type
    IgG Antibody Products ScFv Antibody Products Mouse Antibody Products Humanized Antibody Products Neutralizing Antibody Products Rabbit Monoclonal Antibody Products Fab Antibody Products ADCC Enhanced Antibody Products Antibody Magnetic Beads ScFv-Fc Chimera Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    MOB-1305z Mouse Anti-IFNAR1 Recombinant Antibody (MOB-1305z) ELISA, WB, IP, IF, IHC, FC Mouse IgG1, κ
    HPAB-J0126-YC Human Anti-IFNAR1 Recombinant Antibody (clone ch64G12) Inhib, FuncS Chimeric (mouse/human) IgG4
    HPAB-J0127-YC Human Anti-IFNAR1 Recombinant Antibody (clone H2K1) FC, IHC, ELISA Humanized (mouse/human) IgG
    HPAB-J0297-YC Human Anti-IFNAR1 Recombinant Antibody (clone H3K1-G4) Inhib Humanized (mouse/human) IgG4
    VS3-CJ707 Rabbit Anti-IFNAR1 Recombinant Antibody (VS3-CJ707) WB, IHC, IP, FC Rabbit IgG

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    For Research Use Only. Not For Clinical Use.

    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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