Human Anti-IFNAR1 Recombinant Antibody (clone S5B4) (CAT#: HPAB-0159-CN)
Antibody S5B4 is a novel human antibody that specifically binds to human IFNAR1, which can inhibit the type I interferon-mediated cell signaling pathway.
Specific Inquiry
FC
Figure 1 IFNAR blockade during cART reduces cART-resistant HIV-1 reservoirs.
Hu-mice infected with HIV-1 were treated with cART from 4 to 12 wpi. From 7 to 10 wpi, the cART-treated mice were injected with α-IFNAR1 antibody or isotype control mIgG2a antibody.
Cheng, L., Ma, J., Li, J., Li, D., Li, G., Li, F., ... & Tsao, L. C. (2017). Blocking type I interferon signaling enhances T cell recovery and reduces HIV-1 reservoirs. The Journal of clinical investigation, 127(1), 269-279.
Specifications
- Immunogen
- Recombinant hIFNARl-his
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human IFNAR1
- Species Reactivity
- Human
- Clone
- S5B4
- Applications
- FC
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The IFNAR1 antibody has been reported in applications of Flow Cytometry.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1305z-F(E) | Recombinant Anti-Human IFNAR1 Antibody Fab Fragment | WB, IF, FuncS | Fab |
| HPAB-0203CQ-F(E) | Human Anti-IFNAR1 Recombinant Antibody (clone H3K1); Fab Fragment | ELISA, FC, Inhib | Humanized Fab |
| HPAB-J0126-YC-F(E) | Human Anti-IFNAR1 Recombinant Antibody (clone ch64G12); Fab Fragment | ELISA, FC | Chimeric (mouse/human) Fab |
| HPAB-J0127-YC-F(E) | Human Anti-IFNAR1 Recombinant Antibody (clone H2K1); Fab Fragment | ELISA, FC | Humanized (mouse/human) Fab |
| HPAB-J0297-YC-F(E) | Human Anti-IFNAR1 Recombinant Antibody (clone H3K1-G4); Fab Fragment | ELISA, FC, Inhib | Humanized (mouse/human) Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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