Recombinant Rabbit Anti-IL1A Capture Antibody (clone R09-1M1) (CAT#: VS3-WK1706)

This antibody is a rabbit recombinant antibody against human IL1A. It was developed by immunization of rabbit with recombinant human IL1A protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. The sandwich ELISA was established using matched antibody pair R09-1M1 and R07-4C2. The clone R09-1M1 can be used as a capture antibody in ELISA analysis to identify human IL1A.

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Custom Production

We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
RNA Expression

Specifications

  • Immunogen
  • Recombinant human IL1A protein
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human IL1A
  • Species Reactivity
  • Human
  • Clone
  • R09-1M1
  • Applications
  • ELISA
  • Conjugate
  • Unconjugated

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Protein A affinity purified
  • Purity
  • >95% as determined by SDS-PAGE
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • 0.01M PBS, pH 7.2
  • Storage
  • Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
  • Shipping
  • Ice packs

Target

  • Alternative Names
  • Interleukin 1 Alpha
  • Long Name
  • Interleukin 1 Alpha
  • Sequence Similarities
  • Belongs to the IL-1 family.
  • Cellular Localization
  • Cytoplasm, Nucleus, Secreted
  • Post Translation Modifications
  • Acetylated within its nuclear localization sequence, which impacts subcellular localization.
    Proteolytic processed by CAPN1 in a calcium-dependent manner. Cleavage from 31 kDa precursor to 18 kDa biologically active molecules.
    Phosphorylated. Phosphorylation greatly enhances susceptibility to digestion and promotes the conversion of pre-IL1A alpha to the biologically active IL1A.
  • Function
  • Cytokine constitutively present intracellularly in nearly all resting non-hematopoietic cells that plays an important role in inflammation and bridges the innate and adaptive immune systems. After binding to its receptor IL1R1 together with its accessory protein IL1RAP, forms the high affinity interleukin-1 receptor complex. Signaling involves the recruitment of adapter molecules such as MYD88, IRAK1 or IRAK4.

Recommended Products

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "IL1A"

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CAT Product Name Application Type
NABL-094 Recombinant Anti-human IL1A VHH Single Domain Antibody WB, ELISA, IHC, FC, FuncS Llama VHH

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