Recombinant Anti-ITGB2 Vesicular Antibody, EV Displayed (VS-0425-YC336)
CAT#: VS-0425-YC336
The Recombinant Anti-ITGB2 Vesicular Antibody, EV Displayed (VS-0425-YC336) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ITGB2-expressed cells or tissues. The ITGB2 is an integrin beta chain crucial for immune response, with defects causing leukocyte adhesion deficiency.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16894/202_B8_2_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line EFO-21
Immunofluorescent staining of human cell line EFO-21 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16894/131_C9_1_blue_red_green.jpg
Subcellular Location
Figure 3 IF staining of human cell line BJ
Immunofluorescent staining of human cell line U-4 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16894/1842_G1_63_blue_red_green.jpg
RNA Expression
Figure 4 RNA cell line category: Group enriched (THP-1, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160255-ITGB2
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ITGB2
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Integrin subunit beta 2
- Biological Process
- Cell adhesion, Phagocytosis
- Molecular Function
- Integrin, Receptor
- Cellular Localization
- Plasma membrane, Rods & Rings
- Introduction
- This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.
- Alternative Names
- CD18, LFA-1, MAC-1, MFI7
- Gene ID
- 3689
- UniProt ID
- P05107
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Datasheet
MSDS
COA
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| TAB-1582CL-F(E) | Anti-Human ITGB2 Recombinant Antibody Fab Fragment (Hu23F2G (also known as LeukArrest and Rovelizumab)) | Inhib | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1581CL | Anti-Human ITGB2 Recombinant Antibody (23F2G) | Inhib | |
| TAB-1581CL-S(P) | Anti-Human ITGB2 Recombinant Antibody scFv Fragment (23F2G) | Inhib | |
| TAB-1581CL-F(E) | Anti-Human ITGB2 Recombinant Antibody Fab Fragment (23F2G) | Inhib |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0108CT | Recombinant Mouse anti-Human ITGB2 Monoclonal antibody (NFN-259) | FC, FuncS, IP, WB | |
| HPAB-1874-FY | Human Anti-ITGB2 Recombinant Antibody (clone NA-8) | Block | Human IgG1 |
| FAMAB-1192CQ | Mouse Anti-ITGB2 Recombinant Antibody (clone YFC 118.12) | Block, FC | Mouse IgG1 |
| FAMAB-1193CQ | Human Anti-ITGB2 Recombinant Antibody (clone 1B4) | IP, RIA, ELISA, FC, IF | Human IgG1 |
| VS3-CJ398 | Mouse Anti-ITGB2 Recombinant Antibody (VS3-CJ398) | WB, IHC-P | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0298MZ | Chicken Anti-ITGB2 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1590CQ | Recombinant Mouse Anti-ITGB2 Antibody (MEM-48) | BL, FC, IHC-Fr, IHC-P, IP, WB | IgG1 |
| NEUT-1591CQ | Recombinant Mouse Anti-ITGB2 Antibody (TS1/18) | BL, FC, ICC, IF, IHC, WB | IgG1 |
| NEUT-1592CQ | Recombinant Mouse Anti-ITGB2 Antibody (YFC118.12) | FC, BL | IgG1, κ |
| NEUT-1593CQ | Recombinant Mouse Anti-ITGB2 Antibody (MEM-148) | FC, IP, WB, BL, FuncS | IgG1 |
| NEUT-1594CQ | Recombinant Hamster Anti-Itgb2 Antibody (2E6) | BL, ICC, IP, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1884 | Hi-Affi™ Recombinant Rabbit Anti-ITGB2 Monoclonal Antibody (DS1884AB) | IP, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0203CQ-F(E) | Mouse Anti-ITGB2 Recombinant Antibody (clone 60.3); Fab Fragment | ELISA, WB, Block | Mouse Fab |
| FAMAB-0204CQ-F(E) | Human Anti-ITGB2 Recombinant Antibody (clone h60.3); Fab Fragment | ELISA, WB, Block | Human Fab |
| HPAB-0801-CN-F(E) | Recombinant Mouse Anti-ITGB2 Antibody Fab Fragment (CBCNC1) | ELISA, IHC | Mouse Fab |
| HPAB-1769-FY-S(P) | Human Anti-ITGB2 Recombinant Antibody (clone D2-57); Fab Fragment | ELISA | Human Fab |
| HPAB-1770-FY-S(P) | Human Anti-ITGB2 Recombinant Antibody (clone DX-2001); Fab Fragment | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0203CQ-S(P) | Mouse Anti-ITGB2 Recombinant Antibody (clone 60.3); scFv Fragment | ELISA, WB, Block | Mouse scFv |
| FAMAB-0204CQ-S(P) | Human Anti-ITGB2 Recombinant Antibody (clone h60.3); scFv Fragment | ELISA, WB, Block | Human scFv |
| HPAB-1207WJ-S(P) | Human Anti-ITGB2 Recombinant Antibody (clone pxCD18-7T3); scFv Fragment | ELISA | Human scFv |
| HPAB-1292WJ-S(P) | Rat Anti-ITGB2 Recombinant Antibody (clone YFC51.1); scFv Fragment | ELISA, FC | Rat scFv |
| HPAB-1293WJ-S(P) | Human Anti-ITGB2 Recombinant Antibody (clone LDP-01); scFv Fragment | ELISA, FC | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-044 | Afuco™ Anti-ITGB2 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-044) | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY153 | CytoStream™ Mouse Anti-ITGB2 Recombinant Antibody (clone WT.3) | FC, Block, IHC, IP | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY138 | Human Anti-ITGB2 (clone Hu23F2G) scFv-Fc Chimera | Block, FC, IHC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3657 | Anti-ITGB2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3658 | Anti-Mouse ITGB2 Immunohistochemistry Kit | IHC |
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