Recombinant Anti-TLR4 Vesicular Antibody, EV Displayed (VS-0425-YC502) (CAT#: VS-0425-YC502)

• Application
• ELISA, FC, Neut, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• TLR4

• Host Animal
• Rat

• Antibody Isotype
• IgG

• Species Reactivity
• Rat

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Toll like receptor 4

• Biological Process
• Immunity, Inflammatory response, Innate immunity

• Molecular Function
• Receptor

• Cellular Localization
• Golgi apparatus, Plasma membrane

• Introduction
• Enables lipopolysaccharide binding activity and phosphatidylinositol 3-kinase binding activity. Involved in several processes, including cellular response to mechanical stimulus; detection of stimulus involved in sensory perception of pain; and regulation of macromolecule metabolic process. Located in cell surface. Used to study several diseases, including carotid stenosis; ileitis; neuropathy (multiple); obesity; and renal fibrosis. Biomarker of several diseases, including kidney failure (multiple); liver disease (multiple); pancreatitis (multiple); perinatal necrotizing enterocolitis; and pulpitis. Human ortholog(s) of this gene implicated in several diseases, including allergic contact dermatitis (multiple); artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); and lung disease (multiple). Orthologous to human TLR4 (toll like receptor 4).

• Gene ID
• 29260

Select a product category from the dropdown menu below to view related products.