Recombinant Anti-TM4SF5 Vesicular Antibody, EV Displayed (VS-0425-YC101)
CAT#: VS-0425-YC101
The Recombinant Anti-TM4SF5 Vesicular Antibody, EV Displayed (VS-0425-YC101) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to TM4SF5-expressed cells or tissues. The TM4SF5 is a protein involved in cell regulation signal transduction, associated with tumor cell growth.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line Hep G2
Immunofluorescent staining of human cell line Hep G2 shows localization to nucleoplasm & cell junctions.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55674/1144_G10_1_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Group enriched (CACO-2, Hep G2, OE19)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142484-TM4SF5
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Recombinant Antibody
- Application
- ELISA, FC, Inhib, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- TM4SF5
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Transmembrane 4 L six family member 5
- Biological Process
- Cell cycle
- Cellular Localization
- Plasma membrane, Cell Junctions, Nucleoplasm
- Introduction
- The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence and structure to transmembrane 4 superfamily member 1. It may play a role in cell proliferation, and overexpression of this protein may be associated with the uncontrolled growth of tumour cells.
- Gene ID
- 9032
- UniProt ID
- O14894
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Datasheet
MSDS
COA
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See other products for "TM4SF5"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-693CT | Mouse Anti-TM4SF5 Recombinant Antibody (TAB-693CT) | ELISA, FC, Inhib | Mouse IgG |
| TAB-694CT | Human Anti-TM4SF5 Recombinant Antibody (TAB-694CT) | ELISA, FC, Inhib | Human antibody |
| TAB-695CT | Human Anti-TM4SF5 Recombinant Antibody (TAB-695CT) | ELISA, FC, Inhib | Human antibody |
| TAB-696CT | Human Anti-TM4SF5 Recombinant Antibody (TAB-696CT) | ELISA, FC, Inhib | Human antibody |
| TAB-697CT | Human Anti-TM4SF5 Recombinant Antibody (TAB-697CT) | ELISA, FC, Inhib | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0350MC | Rabbit Anti-TM4SF5 Polyclonal Antibody | ELISA, IHC | Rabbit IgG |
| HPAB-N0263-YC | Human Anti-TM4SF5 Recombinant Antibody (HPAB-N0263-YC) | ELISA, FC, Inhib, FuncS | Humanized IgG |
| HPAB-0103-WJ | Human Anti-TM4SF5 Recombinant Antibody (HPAB-0103-WJ) | ELISA, SPR, IHC, Inhib, IF, WB | Human IgG2a, κ |
| FAMAB-0706WJ | Mouse Anti-TM4SF5 Recombinant Antibody (clone mEC2-C) | ELISA, WB | Mouse IgG |
| FAMAB-0707WJ | Human Anti-TM4SF5 Recombinant Antibody (clone hEC2-C-1) | ELISA, WB | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0263-YC-S(P) | Human Anti-TM4SF5 Recombinant Antibody; scFv Fragment (HPAB-N0263-YC-S(P)) | ELISA, FC, Inhib, FuncS | Humanized scFv |
| HPAB-0103-WJ-S(P) | Mouse Anti-TM4SF5 Recombinant Antibody; scFv Fragment (HPAB-0103-WJ-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0263-YC-F(E) | Human Anti-TM4SF5 Recombinant Antibody; Fab Fragment (HPAB-N0263-YC-F(E)) | ELISA, FC, Inhib, FuncS | Humanized Fab |
| HPAB-0103-WJ-F(E) | Human Anti-TM4SF5 Recombinant Antibody; Fab Fragment (HPAB-0103-WJ-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY172 | Human Anti-TM4SF5 (clone hEC2-C-2) scFv-Fc Chimera | ELISA, WB, IP, IF, IHC | Human IgG1, scFv-Fc |
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