B cell lymphoma A20-HL Idiotype & CD3

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For Research Use Only. Not For Clinical Use.


Background

CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). It is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains.
The Id of the surface Ig of malignant B lymphocytes is a tumor-specific Ag.
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