Anti-Human CD3 Recombinant Antibody Fab Fragment (VH1/VK1) (CAT#: TAB-085LC-F(E))

TAB-085LC is a recombinant monoclonal antibody targeting CD3. It is a humanized antibody with potential applications in treating autoimmune disorders, infectious diseases, and transplant rejection. This antibody is valuable in pharmaceutical use due to its humanized and de-immunized framework regions (FRs), which minimize the risk of a HAHA/HAMA response. Additionally, it enhances cell signaling activities to achieve positive immunological effects, while preserving cell-surface binding and preventing improper disulfide bond formation. Furthermore, it improves pharmaceutical stability. TAB-085LC-F(E) antibody is the Fab fragment antibody form of TAB-085LC antibody. Fab fragments, the antigen-binding domains of an antibody molecule, consist of two amino acid chains composed of VH+CH1 and VL+CL domains.