EGFR & ErbB-3
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Loading...- Cetuximab (Gly-015CL)
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- CAS number: 205923-56-4
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- Host Species: Human
- Specificity: Human
- Type: Chimeric antibody (mouse/human)
- Classification: Fc glycosylation/High-mannose glycosylated
- Glycosylation site: Asn297 in Fc region
- Glycoform (ratio): Man3GlcNAc2
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- Host Species: Human
- Specificity: Human
- Type: Chimeric antibody (mouse/human)
- Classification: Fc glycosylation/High-mannose glycosylated
- Glycosylation site: Asn297 in Fc region
- Glycoform (ratio): Man3GlcNAc2
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- Host Species: Human
- Specificity: Human
- Type: Humanized antibody
- Classification: Fc glycosylation
- Glycosylation site: Asn297 in Fc region
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Classification: Non-glycosylated
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For Research Use Only. Not For Clinical Use.
Background
EGFR: Functions as a receptor tyrosine kinase controlling cell growth and differentiation. It activates multiple signaling cascades upon ligand binding. The protein is widely expressed in epithelial tissues. Mutations drive oncogenesis.


Bladder Cancer
Non-small Cell Lung Cancer
Pancreatic Cancer
Hepatocellular Carcinoma
Cushing Syndrome
JAK-STAT Signaling Pathway