Products

Recombinant Anti-EGFR Antibody (Fc glycosylation/High-mannose glycosylated) (Gly-055LC)

This product is a chimeric (mouse/human) monoclonal antibody with N-glycosylation site Asn297 in the Fc region by which the antibody has modulated ADCC. The antibody specifically binds human EGFR and can be potentially used in the treatment of colorectal cancer and head and neck cancer.      

  • Datasheet

Glyco-engineering
Classification
Fc glycosylation/High-mannose glycosylated
Glycosylation site
Asn297 in Fc region
Glycoform (ratio)
Man3GlcNAc2
Glycosylation Type
N-glycosylation
Activity
Modulate ADCC
Specifications
Target
EGFR (Epidermal growth factor receptor)
Host Animal
Human
Derivation
Chimeric (mouse/human)
Type
Chimeric antibody (mouse/human)
Specificity
Human
Clone
Glyco C225
Applications
ELISA
Target
Alternative Names
EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2
Related Disease
Colorectal cancer and Head and neck cancer
Entrez Gene ID
1956
UniProt ID
P00533

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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