Recombinant Anti-Human EGFR Antibody (Fc glycosylation/High-mannose glycosylated) (CAT#: Gly-055LC)

This product is a chimeric (mouse/human) monoclonal antibody with N-glycosylation site Asn297 in the Fc region by which the antibody has modulated ADCC. The antibody specifically binds human EGFR and can be potentially used in the treatment of colorectal cancer and head and neck cancer.

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  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression

Glyco-engineering

  • Glycosylation site
  • Asn297 in Fc region
  • Glycoform (ratio)
  • Man3GlcNAc2
  • Glycosylation Type
  • N-glycosylation
  • Activity
  • Modulate ADCC

Specifications

  • Target
  • EGFR (Epidermal growth factor receptor)
  • Host Species
  • Human
  • Derivation
  • Chimeric (mouse/human)
  • Type
  • Chimeric antibody (mouse/human)
  • Specificity
  • Human
  • Clone
  • Glyco C225
  • Applications
  • ELISA

Target

  • Alternative Names
  • EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1;
  • Related Disease
  • Colorectal cancer and Head and neck cancer

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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