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EGFR

Anti-EGFR Products

Cetuximab (Gly-015CL)
- CAS number: 205923-56-4
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Recombinant Anti-Human EGFR Antibody (Fc glycosylation/High-mannose glycosylated) (Gly-055LC)
- Host Species: Human
- Specificity: Human
- Type: Chimeric antibody (mouse/human)
- Glycosylation site: Asn297 in Fc region
- Glycoform (ratio): Man3GlcNAc2
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Recombinant Anti-Human EGFR Antibody (Fc glycosylation) (Gly-144LC)
- Host Species: Human
- Specificity: Human
- Type: Humanized antibody
- Glycosylation site: Asn297 in Fc region
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Recombinant Anti-Human EGFR Antibody (Non-glycosylated) (Gly-167LC)
- Host Species: Human
- Specificity: Human
- Type: Human antibody
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Recombinant Anti-Human EGFR Antibody (Fc glycosylation/High-mannose glycosylated) (Gly-055LC-1)
- Host Species: Human
- Specificity: Human
- Type: Chimeric antibody (mouse/human)
- Glycosylation site: Asn297 in Fc region
- Glycoform (ratio): Man3GlcNAc2
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For Research Use Only. Not For Clinical Use.

Background

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

Related Diseases

Bladder Cancer

Non-small Cell Lung Cancer

Pancreatic Cancer

Hepatocellular Carcinoma

Cushing Syndrome

Related Signaling Pathways

JAK-STAT Signaling Pathway