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EGFR

EGFR (Epidermal growth factor receptor) is a transmembrane glycoprotein that is a member of the protein kinase superfamily. EGFR is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of EGFR to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in EGFR are associated with lung cancer.
  • Cetuximab (Gly-015CL)

    • CAS number: 205923-56-4

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