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For Research Use Only. Not For Clinical Use.
Cancer-related genes, Plasma proteins
Intracellular, Secreted (different isoforms)
Cell type enhanced (Proximal enterocytes, Distal enterocytes, Paneth cells)
Group enriched (classical monocyte, intermediate monocyte, non-classical monocyte, myeloid DC, T-reg)
Cell line enhanced (ASC TERT1, CAPAN-2, OE19, SK-MEL-30)
Probably forms homo- or heterodimers. Interacts with DMBT1 (By similarity). Interacts with CD6 and ALCAM (PubMed:24945728). Forms a complex with the ITGA3, ITGB1 and CSPG4. Interacts with LGALS3BP, LYPD3, CYHR1 and UACA. Interacts with TRIM16; this interaction mediates autophagy of damage endomembranes. Interacts with cargo receptor TMED10; the interaction mediates the translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and thereby secretion (PubMed:32272059).
IgE-binding protein