Anti-MME Recombinant Antibody Products

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Anti-MME Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs specializes in providing high-quality anti-MME antibodies for biomedical research. We prioritize precision and reliability to support scientific advancements. Committed to excellence, we ensure researchers have dependable tools to drive innovation and discoveries.

MME: A Crucial biomarker in Cancer and Alzheimer's disease

Membrane metallo-endopeptidase (MME), popularly known as neutral endopeptidase (NEP) or CD10, is a type - II integral membrane protein distributed throughout various body tissues, including the kidneys, lungs, and nervous system. Functioning as a zinc - dependent endopeptidase, it cleaves peptide hormones and neurotransmitters to maintain biochemical balance. MME is involved in multiple diseases: it helps regulate blood pressure, with malfunction contributing to hypertension; participates in amyloid-β peptide metabolism, affecting Alzheimer's disease progression; and serves as a biomarker in some cancers, influencing tumor cell proliferation and metastasis. As such, MME is a significant target for developing new therapies.

Alternative Names

NEP; SFE; CD10; CALLA; CMT2T; SCA43

Background

The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.

Anti-MME rAb Products

At Creative Biolabs, our mission is to supply top - tier anti - MME recombinant antibodies for target - based drug research. Our commitment lies in delivering products that are not only reliable but also highly effective. We aim to accelerate scientific progress and actively support researchers in their pursuit of new discoveries.

Customer Reviews

Excellent

J**ue
Mouse Anti-MME Recombinant Antibody (clone 60656-7H5) (Cat#: HPAB-0311-YJ)

This antibody was applied in IHC, ELISA, and WB to detect MME in kidney, prostate tissues, and cancer cell lines. It showed strong specificity in IHC, clear bands in WB, and consistent results in ELISA. With reliable performance across assays, it's a valuable asset for MME research in normal and pathological contexts.

3/Mar/2023

Excellent

W**te
Mouse Anti-MME Recombinant Antibody (clone 24C6) (Cat#: MOB-1454z)

We evaluated the antibody using FC and IF to detect MME (CD10) in human leukemia and epithelial cell lines. It demonstrated high specificity and strong signal intensity, clearly differentiating positive from negative cells. In IF, it provided sharp membrane staining with low background. With consistent, reproducible results, it's an ideal option for MME research in cancer biology and stem cell studies.

27/Sep/2024

rAb Production

With extensive expertise in expression vector optimization, transfected cell line selection, and antibody purification, we deliver comprehensive, end-to-end solutions for antibody production. Our services cover the entire process, from gene synthesis to final antibody generation, ensuring high-yield and efficiency. By utilizing advanced screening and purification technologies, we tailor our approach to meet diverse research needs. Our streamlined workflows enhance production quality and reliability, supporting scientific advancements with customized solutions that drive more consistent and reproducible results in various applications.

Featured Anti-MME Recombinant Antibody Production Platforms
Fig.1 Milligram-scale recombinant antibody production.

Fig.2 Gram-scale recombinant antibody production.

rAb Modalities

Creative Biolabs specializes in delivering a wide range of recombinant antibody formats designed for applications from basic research to drug discovery. We prioritize precision engineering to ensure exceptional quality, reliability, and performance, meeting diverse scientific needs. With a commitment to innovation and adaptability, we accelerate biomedical advancements. By continuously refining our technologies and expanding our portfolio, we empower researchers with cutting-edge tools for therapeutic development and advanced scientific exploration.

Fig.3 Full Length Anti-MME Recombinant Antibody Production and Modalities.

For more information about our anti-MME recombinant antibodies or any inquiries, feel free to reach out us. Our expert team is ready to provide personalized support and professional guidance. We are dedicated to delivering reliable solutions that facilitate scientific breakthroughs. Count on us for a seamless experience and the resources you need to achieve research success.