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RGMA

Anti-RGMA Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


The RGMA binding proteins, particularly monoclonal antibodies have the ability to bind to RGMA, and therefore neutralize the function of RGMA, for use in the treatment of retinal nerve fiber layer (RNFL) degeneration.
RGMA
Predicted location

Intracellular, Secreted (different isoforms)

Single cell type specificity

Cell type enhanced (Astrocytes, Leydig cells, Peritubular cells, Skeletal myocytes, Prostatic glandular cells, Squamous epithelial cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (AF22, BEWO, MOLT-4, NTERA-2, REH)

Interaction

Interacts with NEO1, BMP2 and BMP4.

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