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RGMA

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For Research Use Only. Not For Clinical Use.


This gene encodes a member of the repulsive guidance molecule family. The encoded protein is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. This protein may also function as a tumor suppressor in some cancers. Alternate splicing results in multiple transcript variants.
RGMA
Predicted location

Intracellular, Secreted (different isoforms)

Single cell type specificity

Cell type enhanced (Astrocytes, Leydig cells, Peritubular cells, Skeletal myocytes, Prostatic glandular cells, Squamous epithelial cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (AF22, BEWO, MOLT-4, NTERA-2, REH)

Interaction

Interacts with NEO1, BMP2 and BMP4.

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