Afuco™ Anti-RGMA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-421CQ)

CAT#: AFC-TAB-421CQ

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to RGMA. It is a human monoclonal antibody that can be potentially used in the treatment of Multiple Sclerosis.

Gene Expression
Figure 1 IF staining of human cell line RH-30 Figure 2 IF staining of human cell line U-2 OS Figure 3 Cerebral cortex Figure 4 Colon Figure 5 Liver Figure 6 Kidney Figure 7 Testis Figure 8 RNA cell line category: Cell line enhanced (AF22, BEWO, MOLT-4, NTERA-2, REH)

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • ADCC enhanced antibody
  • Specificity
  • Human RGMA
  • Species Reactivity
  • Human
  • Applications
  • ELISA, IHC, FC, IP, IF, FuncS
  • Conjugate
  • Unconjugated
  • Generic Name
  • Elezanumab
  • Related Disease
  • Multiple Sclerosis

Product Property

  • Purity
  • >95% by SDS-PAGE
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • RGM
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Breast cancer biomarkers at key points during disease progression
Insightful Antibody for Neuroscience
The Elezanumab antibody is superb for neuroscience research. We employed it in studying RGMA's interference in neuronal outgrowth, and the results were consistent and enlightening. It truly gave us novel insights into neural pathways. Its ADCC enhancement makes it even more applicable in understanding immune responses in brain tissues.
Breast cancer biomarkers at key points during disease progression
Perfect for RGMA Pathway Studies
Elezanumab has significantly aided our studies centered around the RGMA signaling pathway. Its specificity ensured that our assays focused directly on target interactions, eliminating background noise. This level of precision enhances our understanding of cellular processes tied to neurodevelopment.
Breast cancer biomarkers at key points during disease progression
Outstanding Tool for Science
Elezanumab stands out as an excellent research tool. We utilized it in both ELISA and IHC, with stellar outcomes each time. Its contribution to understanding disease pathways in a non-clinical context cannot be understated.

Q&As

  1. What is the specific application of Elezanumab in laboratory research?

    A: Elezanumab is primarily used in research to study its effects on the RGMA protein. This antibody has applications in ELISA, immunohistochemistry, flow cytometry, and more functional studies. Researchers use it to investigate neural pathways and potential mechanisms tied to neurodegenerative processes.

  2. Can Elezanumab be employed in cancer research, and if so, how?

    A: Yes, Elezanumab's properties make it useful in cancer research, particularly in understanding the RGMA protein's role. By blocking RGMA, it may help delineate pathways involved in cell growth or metastasis, potentially unveiling targets for therapeutic strategies in oncology.

  3. Is Elezanumab suitable for use in proteomics, and how?

    A: Yes, Elezanumab is valuable in proteomics for analyzing RGMA-related pathways and protein interactions. Through techniques like immunoprecipitation and Western blotting, researchers can gain insights into RGMA's role in cellular signaling networks.

View the frequently asked questions answered by Creative Biolabs Support.

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Related Signaling Pathways

Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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COA

Certificate of Analysis Lookup

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Protocol & Troubleshooting

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

See other products for "RGMA"

Select a product category from the dropdown menu below to view related products.

CAT Product Name Application Type
MOR-3059 Hi-Affi™ Recombinant Rabbit Anti-RGMA Monoclonal Antibody (DS3059AB) WB, ICC, IF IgG
CAT Product Name Application Type
TAB-421CQ Anti-Human RGMA Recombinant Antibody (TAB-421CQ) ELISA, IHC, FC, IP, IF, FuncS IgG1, λ1
CAT Product Name Application Type
VS-0425-FY173 Human Anti-RGMA scFv-Fc Chimera (VS-0425-FY173) ELISA, Inhib Human IgG1, scFv-Fc
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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