RPS6KB1

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Anti-RPS6KB1 Products

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    • Specificity: Human Ribosomal Protein S6 Kinase Beta 1
    • Target: RPS6KB1
    • Application: ELISA
    • Sample Type: Serum, Plasma, Cell culture supernatant, Cell lysate, Tissue lysate
    • Assay Type: Sandwich ELISA
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For Research Use Only. Not For Clinical Use.


Background

P70S6 Kinase is a downstream effector of the mTOR signaling pathway. It phosphorylates the S6 ribosomal protein, thereby increasing the translation of specific mRNA subsets. It is a fundamental regulator of protein synthesis, cell growth, and cellular metabolism.
Protein class

Enzymes, Metabolic proteins, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enriched (MCF7)

Interaction

Interacts with PPP1R9A/neurabin-1 (By similarity). Interacts with RPTOR (PubMed:12150926). Interacts with IRS1 (PubMed:18952604). Interacts with EIF3B and EIF3C (PubMed:16286006). Interacts with TRAF4 (PubMed:12801526). Interacts with POLDIP3 (PubMed:15341740). Interacts (via N-terminus) with IER5 (PubMed:26496226).

Molecular function

Kinase, Serine/threonine-protein kinase, Transferase

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