TCF4

AbPlus Formats

Anti-TCF4 Recombinant Antibody Products

Mouse Anti-TCF4 Recombinant Antibody (clone 32H10) (MOB-3599z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, FC
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Rabbit Anti-TCF4 Polyclonal Antibody (MRO-2212-CN) (MRO-2212-CN)
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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Mouse Anti-TCF4 Recombinant Antibody (clone 4D4C4) (VS3-XY1491)
- Type: Mouse IgG1
- Application: FC
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CytoStream™ Rabbit Anti-TCF4 Recombinant Antibody (VS13-YC1147) (VS13-YC1147)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC-P, FC, ChIP
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Mouse Anti-TCF4 Recombinant Antibody (clone 7B1B3) (VS7-0425-WR958)
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: FC
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Anti-TCF4 Immunohistochemistry Kit (VS-0325-XY2256)
- Species Reactivity: Human, Mouse, Rat
- Target: TCF4
- Application: IHC
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For Research Use Only. Not For Clinical Use.

Transcription factor that binds to the immunoglobulin enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5-CANNTG-3). Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription (By similarity). Preferentially binds to either 5-ACANNTGT-3 or 5-CCANNTGG-3.

Protein class

Disease related genes, Human disease related genes, Transcription factors

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Inhibitory neurons, Adipocytes, Oligodendrocyte precursor cells, Endothelial cells, Oligodendrocytes)

Immune cell specificity

Group enriched (plasmacytoid DC, memory B-cell, naive B-cell)

Cell line specificity

Cell line enhanced (HDLM-2, SH-SY5Y)

Interaction

Efficient DNA binding requires dimerization with another bHLH protein. Forms homo- or heterooligomers with myogenin. Interacts with HIVEP2. Interacts with NEUROD2 (By similarity). Interacts with AGBL1. Interacts with BHLHA9.

Molecular function

Activator, DNA-binding

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Related Diseases

Breast Cancer