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    Anti-Human ACVR2A Recombinant Antibody scFv Fragment (APE2666) (CAT#: TAB-0364CL-S(P))

    The anti- ActRII antibody specifically target an activin receptor I, which is related to the regulation of muscle growth. By effectively neutralizing the ActllR activity, the specific antibody can be used in the treatment of muscle wasting, and in the regulation of muscle growth.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of cell line RH-30
    Figure 1 IF staining of cell line RH-30
    (Immunofluorescent staining of cell line RH-30 shows localization to cytosol.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46997/1150_C7_5_blue_red_green.jpg
    Figure 2 IF staining of cell line RT4
    Figure 2 IF staining of cell line RT4
    (Immunofluorescent staining of cell line RT4 shows localization to cytosol.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46997/1421_G1_4_blue_red_green.jpg
    Figure 3 IHC staining of human rectum
    Figure 3 IHC staining of human rectum
    (Immunohistochemical staining of human rectum shows strong cytoplasmic and membranous positivity in glandular cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46997/ihc_selected.jpg
    Normal Tissue
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Endothelial cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous Neuronal cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear
    Neuropil
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46997/106208_B_7_5.jpg
    Figure 5 Colon
    Figure 5 Colon
    (Endothelial cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/
    membranous
    Glandular cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Peripheral nerve/ganglion
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46997/106208_A_9_3.jpg
    Figure 6 Liver
    Figure 6 Liver
    (Hepatocytes
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46997/106208_A_7_4.jpg
    Figure 7 Kidney
    Figure 7 Kidney
    (Cells in glomeruli
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Cells in tubules
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46997/106208_A_8_5.jpg
    Figure 8 Testis
    Figure 8 Testis
    (Cells in seminiferous ducts
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Leydig cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46997/106208_A_4_6.jpg
    Figure 9 Lymph node
    Figure 9 Lymph node
    (Germinal center cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46997/106208_A_9_8.jpg

    Specifications

    • Host Species
    • Human
    • Specificity
    • Human
    • Clone
    • APE2666
    • Related Disease
    • ActRII-mediated, muscle wasting disorder

    Target

    • Alternative Names
    • ACVR2A; activin A receptor, type IIA

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "Clone APE2666"

    See other products for "ACVR2A"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    Human Antibody Products Mouse Antibody Products IgG Antibody Products Rabbit Monoclonal Antibody Products ScFv Antibody Products Fab Antibody Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    TAB-0361CL Anti-Human ACVR2A Recombinant Antibody (APE2990) ELISA, FuncS, Inhib
    TAB-0362CL Anti-Human ACVR2A Recombinant Antibody (APE2991) ELISA, FuncS, Inhib
    TAB-0361CL-S(P) Anti-Human ACVR2A Recombinant Antibody scFv Fragment (APE2990) ELISA, FuncS, Inhib
    TAB-0362CL-S(P) Anti-Human ACVR2A Recombinant Antibody scFv Fragment (APE2991) ELISA, FuncS, Inhib
    TAB-0363CL-S(P) Anti-Human ACVR2A Recombinant Antibody scFv Fragment (APE2665) ELISA, FuncS, Inhib

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