Anti-Human ADAMTS5 Recombinant Antibody scFv Fragment (7B4.1E11)

CAT#: TAB-0685CLV-S(P)

The anti-ADAMTS5 antibody 7B4.1E11 targets ADAMTS5 that is kind of aggrecanases of which the activities can result in the degradation of the cartilage matrix. By inhibiting ADAMTS5 and thereby reducing the breakdown of extracellular matrix aggrecan in cartilage and other tissues, the antibody can be used in the treatment of disease of cartilage.

Gene Expression
Figure 1 IF staining of human cell line RH-30 Figure 2 IHC staining of human caudate Figure 3 IHC staining of human fallopian tube Figure 4 Colon Figure 5 Kidney Figure 6 Testis Figure 7 Lymph node Figure 8 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, fHDF/TERT166, RH-30, U-87 MG)

Specifications

  • Immunogen
  • ADAMTS4, ADAMTS5
  • Host Species
  • Mouse
  • Specificity
  • Human
  • Species Reactivity
  • Cross-react with cynomolgus and canine ADAMTS5
  • Clone
  • 7B4.1E11
  • Related Disease
  • Diseases of cartilage

Target

  • Alternative Names
  • ADAMTS5; ADAM metallopeptidase with thrombospondin type 1 motif, 5; ADMP-2; ADAM-TS5; ADAMTS-5; ADAMTS11; ADAM-TS 5; ADAMTS-11; ADAM-TS 11
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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