Anti-Human ADAMTS5 Recombinant Antibody scFv Fragment (7B4.1E11)
CAT#: TAB-0685CLV-S(P)
The anti-ADAMTS5 antibody 7B4.1E11 targets ADAMTS5 that is kind of aggrecanases of which the activities can result in the degradation of the cartilage matrix. By inhibiting ADAMTS5 and thereby reducing the breakdown of extracellular matrix aggrecan in cartilage and other tissues, the antibody can be used in the treatment of disease of cartilage.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RH-30
Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30906/if_selected.jpg
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Specifications
- Immunogen
- ADAMTS4, ADAMTS5
- Host Species
- Mouse
- Specificity
- Human
- Species Reactivity
- Cross-react with cynomolgus and canine ADAMTS5
- Clone
- 7B4.1E11
- Related Disease
- Diseases of cartilage
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone 7B4.1E11"
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- Product Name
See other products for "ADAMTS5"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-39 | Recombinant Human Anti-human ADAMTS5 Antibody | ELISA, WB, FC, FuncS | IgG |
| PABL-005 | Mouse Anti-ADAMTS5 Recombinant Antibody (clone 7B4) | Inhib, WB, ELISA, FuncS | Mouse IgG1 |
| PABL-391 | Mouse Anti-ADAMTS5 Recombinant Antibody (PABL-391) | WB, ELISA, FuncS | Mouse IgG2c |
| HPAB-AP227-YC | Mouse Anti-ADAMTS5 Recombinant Antibody (HPAB-AP227-YC) | ELISA | Mouse IgG |
| HPAB-AP228-YC | Human Anti-ADAMTS5 Recombinant Antibody (HPAB-AP228-YC) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-005 | Mouse Anti-ADAMTS5 Recombinant Antibody (clone 7B4); scFv Fragment | WB, ELISA, FuncS | Mouse scFv |
| PSBL-391 | Mouse Anti-ADAMTS5 Recombinant Antibody; scFv Fragment (PSBL-391) | WB, ELISA, FuncS | Mouse scFv |
| HPAB-AP227-YC-S(P) | Mouse Anti-ADAMTS5 Recombinant Antibody; scFv Fragment (HPAB-AP227-YC-S(P)) | ELISA | Mouse scFv |
| HPAB-AP228-YC-S(P) | Human Anti-ADAMTS5 Recombinant Antibody; scFv Fragment (HPAB-AP228-YC-S(P)) | ELISA | Human scFv |
| HPAB-AP229-YC-S(P) | Human Anti-ADAMTS5 Recombinant Antibody; scFv Fragment (HPAB-AP229-YC-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-005 | Mouse Anti-ADAMTS5 Recombinant Antibody (clone 7B4); Fab Fragment | WB, ELISA, FuncS | Mouse Fab |
| PFBL-391 | Mouse Anti-ADAMTS5 Recombinant Antibody; Fab Fragment (PFBL-391) | WB, ELISA, FuncS | Mouse Fab |
| HPAB-AP227-YC-F(E) | Mouse Anti-ADAMTS5 Recombinant Antibody; Fab Fragment (HPAB-AP227-YC-F(E)) | ELISA | Mouse Fab |
| HPAB-AP228-YC-F(E) | Human Anti-ADAMTS5 Recombinant Antibody; Fab Fragment (HPAB-AP228-YC-F(E)) | ELISA | Human Fab |
| HPAB-AP229-YC-F(E) | Human Anti-ADAMTS5 Recombinant Antibody; Fab Fragment (HPAB-AP229-YC-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0684CLV | Anti-Human ADAMTS5 Recombinant Antibody (12F4.1H7) | FuncS | |
| TAB-0685CLV | Anti-Human ADAMTS5 Recombinant Antibody (7B4.1E11) | FuncS |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0692CLV | Anti-Human ADAMTS5 Recombinant Antibody (7B4) | ICC, ELISA | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0693CLV | Humanized Anti-Human ADAMTS5 Recombinant Antibody (12F4.1H7) | FuncS | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC23 | CytoStream™ Rabbit Anti-ADAMTS5 Recombinant Antibody (VS13-YC23) | WB, ICC, IF, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC3 | Recombinant Anti-ADAMTS5 Eliminating Antibody, pH-Sensitive (7B4 var.) | Antigen-Sweeping In Vivo. | Human IgG1 |
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