CytoStream™ Rabbit Anti-ADAMTS5 Recombinant Antibody (VS13-YC23)
CAT#: VS13-YC23
The CytoStream™ Rabbit Anti-ADAMTS5 Recombinant Antibody is specific for human, mouse and rat ADAMTS5. ADAMTS5 is part of a family involved in cartilage degradation by cleaving aggrecan, with unique C-terminal domains and TS motifs, playing a role in osteoarthritis. The anti-ADAMTS5 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/1000).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RH-30
Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30906/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human caudate
Immunohistochemical staining of human caudate shows strong cytoplasmic positivity in glial cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5661/ihc_selected.jpg
Normal Tissue
Figure 3 IHC staining of human fallopian tube
Immunohistochemical staining of human fallopian tube shows strong positivity in cytoplasm and cilia of glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25996/ihc_selected.jpg
Normal Tissue
Figure 4 Colon
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25996/58749_A_9_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25996/58749_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25996/58749_A_4_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25996/58749_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, fHDF/TERT166, RH-30, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000154736-ADAMTS5
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Specifications
- Immunogen
- Recombinant human ADAMTS5, aa 251-500.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat ADAMTS5
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, ICC, IF, FC
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.4) containing 40% Glycerol and 0.1% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/2000
Immunofluorescence (IF-cell): 1/100-1/250
Flow cytometry (FC): 1/1000
Target
- Alternative Names
- ADAM Metallopeptidase With Thrombospondin Type 1 Motif 5; Aggrecanase-2; A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin Type 1 Motif, 5 (Aggrecanase-2); A Disintegrin And Metalloproteinase With Thrombospondin Motifs 11; ADAM-TS 11; ADAM-TS 5; ADAMTS-11; ADAM-TS5; ADAMTS-5;
- Gene ID
- 11096
- UniProt ID
- Q9UNA0
- Long Name
- ADAM Metallopeptidase With Thrombospondin Type 1 Motif 5
- Cellular Localization
- Secreted; Extracellular space; Extracellular matrix
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "ADAMTS5"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-39 | Recombinant Anti-human ADAMTS5 Antibody | ELISA, WB, Dot, FuncS | IgG |
| MHH-39 | Recombinant Human Anti-human ADAMTS5 Antibody | ELISA, WB, FC, FuncS | IgG |
| PABL-005 | Mouse Anti-ADAMTS5 Recombinant Antibody (clone 7B4) | Inhib, WB, ELISA, FuncS | Mouse IgG1 |
| PABL-391 | Mouse Anti-ADAMTS5 Recombinant Antibody (PABL-391) | WB, ELISA, FuncS | Mouse IgG2c |
| MOB-142CQ | Mouse Anti-ADAMTS5 Recombinant Antibody (clone CBLS-195) | ELISA, WB, IP | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-39-F(E) | Recombinant Anti-human ADAMTS5 Antibody Fab Fragment | ELISA, IP, FuncS | Fab |
| PFBL-005 | Mouse Anti-ADAMTS5 Recombinant Antibody (clone 7B4); Fab Fragment | WB, ELISA, FuncS | Mouse Fab |
| HPAB-AP227-YC-F(E) | Mouse Anti-ADAMTS5 Recombinant Antibody; Fab Fragment (HPAB-AP227-YC-F(E)) | ELISA | Mouse Fab |
| HPAB-AP228-YC-F(E) | Human Anti-ADAMTS5 Recombinant Antibody; Fab Fragment (HPAB-AP228-YC-F(E)) | ELISA | Human Fab |
| HPAB-AP229-YC-F(E) | Human Anti-ADAMTS5 Recombinant Antibody; Fab Fragment (HPAB-AP229-YC-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-005 | Mouse Anti-ADAMTS5 Recombinant Antibody (clone 7B4); scFv Fragment | WB, ELISA, FuncS | Mouse scFv |
| HPAB-AP227-YC-S(P) | Mouse Anti-ADAMTS5 Recombinant Antibody; scFv Fragment (HPAB-AP227-YC-S(P)) | ELISA | Mouse scFv |
| HPAB-AP228-YC-S(P) | Human Anti-ADAMTS5 Recombinant Antibody; scFv Fragment (HPAB-AP228-YC-S(P)) | ELISA | Human scFv |
| HPAB-AP229-YC-S(P) | Human Anti-ADAMTS5 Recombinant Antibody; scFv Fragment (HPAB-AP229-YC-S(P)) | ELISA | Human scFv |
| HPAB-AP230-YC-S(P) | Human Anti-ADAMTS5 Recombinant Antibody; scFv Fragment (HPAB-AP230-YC-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0684CLV | Anti-Human ADAMTS5 Recombinant Antibody (12F4.1H7) | FuncS | |
| TAB-0685CLV | Anti-Human ADAMTS5 Recombinant Antibody (7B4.1E11) | FuncS |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0692CLV | Anti-Human ADAMTS5 Recombinant Antibody (7B4) | ICC, ELISA | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0693CLV | Humanized Anti-Human ADAMTS5 Recombinant Antibody (12F4.1H7) | FuncS | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC3 | Recombinant Anti-ADAMTS5 Eliminating Antibody, pH-Sensitive (7B4 var.) | Antigen-Sweeping In Vivo. | Human IgG1 |
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