What range of applications is this CD51 antibody suitable for?

This antibody is highly versatile and has been reported for use in ELISA, Flow Cytometry (FC), Immunoprecipitation (IP), Functional Studies (FuncS), Immunofluorescence (IF), Neutralization (Neut), and Immunocytochemistry (ICC).

What is the host and isotype of this antibody?

This product is a Human monoclonal antibody featuring an IgG1-kappa isotype. It is manufactured as a recombinant protein expressed in Chinese Hamster Ovary (CHO) cells. The antibody is designed to specifically bind to the Integrin alpha V, also known as CD51, ensuring high specificity for your research.

Anti-Human CD51 Recombinant Antibody (TAB-076)

CAT#: TAB-076

Recombinant monoclonal antibody to Integrin CD51. It is a human monoclonal antibody used in the treatment of solid tumors.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line A-431

Immunofluorescent staining of human cell line A-431 shows localization to cytosol & focal adhesion sites.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4856/if_selected.jpg

Subcellular Location Figure 2 IHC staining of human placenta

Immunohistochemical staining of human placenta shows strong cytoplasmic and membranous positivity in trophoblastic cells.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4856/ihc_selected.jpg

Subcellular Location Figure 3 IHC staining of human urinary bladder

Immunohistochemical staining of human urinary bladder shows strong membranous positivity in urothelial cells.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2499/ihc_selected.jpg

Subcellular Location Figure 4 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & focal adhesion sites.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4856/10_E3_1_blue_red_green.jpg

Subcellular Location Figure 5 IF staining of human cell line U-251 MG

Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol & focal adhesion sites.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4856/15_E3_1_blue_red_green.jpg

Normal Tissue Figure 6 Cerebral cortex

Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2499/6125_B_8_5.jpg

Normal Tissue Figure 7 Colon

Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2499/6125_A_9_3.jpg

Normal Tissue Figure 8 Liver

Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2499/6125_A_9_4.jpg

Normal Tissue Figure 9 Placenta

Cytotrophoblasts
Staining: High
Intensity: Strong
Quantity:>75%
Endothelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Syncytiotrophoblasts - cell body
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Syncytiotrophoblasts - microvilli
Staining: High
Intensity: Strong

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2499/6125_A_2_7.jpg

RNA Expression Figure 10 RNA cell line category: Cell line enhanced (RT4, SuSa)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138448-ITGAV

❮

❯

Specifications

Immunogen
The details of the immunogen for this antibody are not available.

Host Species
Human

Derivation
Human

Type
IgG1 - kappa

Specificity
Tested positive against native human antigen.

Species Reactivity
Human

Applications
ELISA, FC, IP, FuncS, IF, Neut, ICC, IHC

MW
145.6 kDa

Related Disease
Solid tumors

Product Property

Purity
Purity >95% by SDS-PAGE.

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

Application Notes
The ITGAV antibody has been reported in applications of ELISA, FC, IP, FuncS, IF, Neut, ICC, IHC.

Target

Alternative Names
integrin alpha-V; CD51; integrin alphaVbeta3

Gene ID
3685

UniProt ID
P06756

REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS

Inquiry

Navs

Customer Review

There are currently no Customer reviews or questions for TAB-076. Click the button above to contact us or submit your feedback about this product.

Breast cancer biomarkers at key points during disease progression

Versatile Antibody For CD51 Research

This human monoclonal antibody against Integrin CD51 is incredibly versatile. We have successfully used it in ELISA, Flow Cytometry, and Immunofluorescence. It recognizes the native human antigen well, making it indispensable for our studies on vitronectin receptors and their role in tumor solid formation.

Q&As

What range of applications is this CD51 antibody suitable for?

A: This antibody is highly versatile and has been reported for use in ELISA, Flow Cytometry (FC), Immunoprecipitation (IP), Functional Studies (FuncS), Immunofluorescence (IF), Neutralization (Neut), and Immunocytochemistry (ICC).
What is the host and isotype of this antibody?

A: This product is a Human monoclonal antibody featuring an IgG1-kappa isotype. It is manufactured as a recombinant protein expressed in Chinese Hamster Ovary (CHO) cells. The antibody is designed to specifically bind to the Integrin alpha V, also known as CD51, ensuring high specificity for your research.

View the frequently asked questions answered by Creative Biolabs Support.

Submit Your Publication

Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

Biosimilar Overview

Please refer to Intetumumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Intetumumab.

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-076.pdf

MSDS

MSDS - TAB-076.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Protocol & Troubleshooting

Immunofluorescence (IF)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

See other products for "ITGAV"

Select a product category from the dropdown menu below to view related products.

CAT	Product Name	Application	Type
MOB-1133z	Mouse Anti-ITGAV Recombinant Antibody (clone 33D12)	ELISA, ICC, IF, IHC, IP, FuncS	Mouse IgG2a

CAT	Product Name	Application	Type
TAB-H01	Anti-Human ITGAV Recombinant Antibody (Abituzumab)	Inhib, Agonist	IgG2 - kappa

CAT	Product Name	Application	Type
PABL-250	Mouse Anti-ITGAV Recombinant Antibody (clone 17E6)	WB, ELISA, FuncS	Mouse IgG

CAT	Product Name	Application	Type
PSBL-250	Mouse Anti-ITGAV Recombinant Antibody (clone 17E6); scFv Fragment	WB, ELISA, FuncS	Mouse scFv

CAT	Product Name	Application	Type
PFBL-250	Mouse Anti-ITGAV Recombinant Antibody (clone 17E6); Fab Fragment	WB, ELISA, FuncS	Mouse Fab

CAT	Product Name	Application	Type
MOB-0242CT	Recombinant Mouse anti-Human ITGAV Monoclonal antibody (24D3)	FC, IHC-Fr, PP

CAT	Product Name	Application	Type
PABX-191-S (P)	Recombinant Mouse Anti-αVβ3 Ectodomain Antibody scFv Fragment (17E6)	Neut, FuncS	scFv

CAT	Product Name	Application	Type
PABX-191-F (E)	Recombinant Mouse Anti-αVβ3 Ectodomain Antibody Fab Fragment (17E6)	Neut, FuncS	Fab

CAT	Product Name	Application	Type
NEUT-1537CQ	Recombinant Mouse Anti-ITGAV Antibody (272-17E6)	Inhib, ICC, IF, BL, FC, ELISA, IP	IgG1

CAT	Product Name	Application	Type
NEUT-1577CQ	Recombinant Mouse Anti-ITGAV Antibody (13C2)	FC, IHC-Fr, ICC, IP, ELISA, Depletion, BL, Adhesion	IgG1, κ

CAT	Product Name	Application	Type
NEUT-1578CQ	Recombinant Mouse Anti-ITGAV Antibody (NKI-M9)	FC, IF, ELISA, BL, IP	IgG2a, κ

CAT	Product Name	Application	Type
NEUT-1579CQ	Recombinant Mouse Anti-ITGAV Antibody (10D5)	IP, FC, BL	IgG2a

CAT	Product Name	Application	Type
NEUT-1580CQ	Recombinant Mouse Anti-ITGAV Antibody (27.1)	ICC, IF, FC, IP, IHC-Fr, BL	IgG1

CAT	Product Name	Application	Type
NEUT-1582CQ	Recombinant Rat Anti-Itgav Antibody (RMV-7)	FC, FuncS, IP, Neut	IgG1, κ

CAT	Product Name	Application	Type
MOR-1880	Hi-Affi™ Recombinant Rabbit Anti-ITGAV Monoclonal Antibody (DS1880AB)	WB, FC	IgG

CAT	Product Name	Application	Type
MRO-0852-CN	Recombinant Rabbit Anti-ITGAV Monoclonal Antibody (CBACN-313)	WB, FC	Rabbit IgG

CAT	Product Name	Application	Type
AFC-TAB-076	Afuco™ Anti-ITGAV ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-076)	ELISA, FC, IP, FuncS, IF, Neut	ADCC enhanced antibody

CAT	Product Name	Application	Type
AFC-TAB-H01	Afuco™ Anti-ITGAV ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H01)	ELISA, IP, FC, FuncS, IF, Neut	ADCC enhanced antibody

CAT	Product Name	Application	Type
HPAB-1767-FY	Human Anti-EPHA2 Recombinant Antibody (clone 12G3)	ADCC	Humanized IgG

CAT	Product Name	Application	Type
HPAB-1767-FY-F(E)	Human Anti-EPHA2 Recombinant Antibody (clone 12G3); Fab Fragment	Cyt, ELISA	Humanized Fab

CAT	Product Name	Application	Type
HPAB-1767-FY-S(P)	Human Anti-EPHA2 Recombinant Antibody (clone 12G3); scFv Fragment	Cyt, ELISA	Humanized scFv

CAT	Product Name	Application	Type
VS-0424-XY160	AbPlus™ Anti-ITGAV Magnetic Beads (13C2)	IP, Protein Purification

CAT	Product Name	Application	Type
VS13-YC600	CytoStream™ Rabbit Anti-ITGAV Recombinant Antibody (VS13-YC600)	WB, ICC, IF, FC	Rabbit IgG

CAT	Product Name	Application	Type
VS-0425-FY88	Human Anti-ITGAV scFv-Fc Chimera (VS-0425-FY88)	ELISA, FC	Human IgG1, scFv-Fc

CAT	Product Name	Application	Type
VS-0425-YC298	Recombinant Anti-ITGAV Vesicular Antibody, EV Displayed (VS-0425-YC298)	ELISA, FC, Neut, Cell-uptake

CAT	Product Name	Application	Type
VS-0525-XY3644	Anti-ITGAV Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS-0525-XY3645	Anti-Rat ITGAV Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS-0525-XY3646	Anti-Mouse ITGAV Immunohistochemistry Kit	IHC

Specific Inquiry

Size:

Conjugation:

Endotoxin:

Purity:

Formats:

Isotype Switching:

Fc Engineering:

Modalities:

Add to compare

Request
Custom Production

See Our Custom Production in Action

Figure 1 Anti-HBV Recombinant Antibody (TAB-147) in SDS-PAGE

Download the full case study

Popular Products

Figure 5 Anti-Human TNFSF11 Antibody (TAB-H18) in DB

Human Anti-TNFSF11 Recombinant Antibody (TAB-H18) (CAT# TAB-H18)
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC

Figure 2 Anti-Human CD22 Recombinant Antibody (TAB-176) in ELISA

Anti-Human CD22 Recombinant Antibody (TAB-176) (CAT# TAB-176)
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC

Figure 2 Anti-SLAMF7 Recombinant Antibody (TAB-743) in WB

Anti-SLAMF7 Recombinant Antibody (Elotuzumab) (CAT# TAB-743)
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC

Figure 5 Anti-RSV glycoprotein F Recombinant Antibody (TAB-709) in ELISA

Anti-RSV glycoprotein F Recombinant Antibody (TAB-709) (CAT# TAB-709)
Application: IF, IP, Neut, FuncS, ELISA, FC, WB

Figure 3 Anti-Human EGFR Antibody (TAB-003) in DB

Anti-Human EGFR Recombinant Antibody (Cetuximab) (CAT# TAB-003)
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC

Figure 3 Llama Anti-human LC-kappa VHH Single Domain Antibody (VHH-His-Cys) (NABG-118-UN) in DB

Llama Anti-human LC-kappa VHH Single Domain Antibody [Biotin] (CAT# NABG-118)
Application: ELISA, WB, BLI, SPR

Figure 10 Recombinant Human Anti-RSV Antibody, HRP (PABL-322-HRP) in Absorption Spectroanalysis

Recombinant Human Anti-RSV Antibody (D25) (CAT# PABL-322)
Application: WB, ELISA, Neut, FuncS

Figure 3 Anti-Human IgE Recombinant Antibody Fab Fragment (CMAB007) in ELISA.

Anti-Human IgE Recombinant Antibody Fab Fragment (CMAB007) (CAT# TAB-034ZJ-F(E))
Application: ELISA

Figure 2 Anti-Human TEM7R Recombinant Antibody (TAB-577CT) in HPLC

Human Anti-PLXDC2 Recombinant Antibody (TAB-577CT) (CAT# TAB-577CT)
Application: ELISA, FC, IHC, IF

Figure 4 Human Anti-TSHR Recombinant Antibody (TAB-191CQ) in ELISA

Human Anti-TSHR Recombinant Antibody (TAB-191CQ) (CAT# TAB-191CQ)
Application: ELISA, WB, Inhib

Figure 5 Human Anti-ASGR Recombinant Antibody (TAB-1013CLV) in ELISA

Human Anti-ASGR Recombinant Antibody (TAB-1013CLV) (CAT# TAB-1013CLV)
Application: FC, FRET, Internalization

Figure 3 Anti-CD27 Recombinant Antibody (MOB-096LC) in DB

Human Anti-CD27 Recombinant Antibody (MOB-096LC) (CAT# MOB-096LC)
Application: ELISA, FuncS, WB

Figure 2 Human Anti-CD70 Recombinant Antibody (HPAB-0102-LSX) in HPLC

Human Anti-CD70 Recombinant Antibody (HPAB-0102-LSX) (CAT# HPAB-0102-LSX)
Application: ELISA, FuncS

Figure 3 Recombinant Anti-IL17A Antibody (HPAB-0208-LSX) in ELISA

Human Anti-IL17A Recombinant Antibody (HPAB-0208-LSX) (CAT# HPAB-0208-LSX)
Application: ELISA, FuncS

Figure 1 Recombinant Human Anti-HHV-5 strain AD169 gB Antibody (EPAF-0438CQ) in SDS-PAGE

Recombinant Human Anti-HHV-5 strain AD169 gB Antibody (ITC88) (CAT# EPAF-0438CQ)
Application: ELISA, Neut

Figure 5 Mouse Anti-VEGFA Recombinant Antibody (clone mAb G6-31) (HPAB-0330CQ) in DB

Mouse Anti-VEGFA Recombinant Antibody (clone mAb G6-31) (CAT# HPAB-0330CQ)
Application: ELISA, IF, Block, FuncS

Figure 2 Recombinant Mouse Anti-EBV gH/gL Antibody (PABC-524) in HPLC

Recombinant Mouse Anti-EBV gH/gL Antibody (E1D1) (CAT# PABC-524)
Application: ELISA, FC, Neut, Inhib

Figure 2 Mouse Anti-MRC2 Recombinant Antibody (HPAB-M0693-YC) in HPLC

Mouse Anti-MRC2 Recombinant Antibody (HPAB-M0693-YC) (CAT# HPAB-M0693-YC)
Application: WB, FuncS

Figure 5 Anti-Human SA Antibody (HPAB-2545LY) in DB

Human Anti-SA Recombinant Antibody (HPAB-2545LY) (CAT# HPAB-2545LY)
Application: ELISA, WB

Figure 2 Human Anti-APS Recombinant Antibody (clone CL1) (HPAB-1960-FY) in HPLC

Human Anti-APS Recombinant Antibody (clone CL1) (CAT# HPAB-1960-FY)
Application: ELISA, Activ, Block

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.