Human Anti-ITGAV Recombinant Antibody (clone 12G3) (CAT#: HPAB-1767-FY)

This product is a recombinant antibody that recognizes ITGAV. The monoclonal antibody 12G3 reacts with the epitope of ITGAV.


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  • Gene Expression
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ADCC

Figure 1 Cell-based ADCC assay of 12G3H11 (anti-EphA2 antibody) and its I332E Fc variant using 50: 1 ratio of effector to A549 target cells.

Figure 1 Cell-based ADCC assay of 12G3H11 (anti-EphA2 antibody) and its I332E Fc variant using 50: 1 ratio of effector to A549 target cells.

ADCC

Figure 2 Cell-based ADCC assay of 12G3H11 (anti-EphA2 antibody) and its I332E Fc variant using 50: 1 ratio of effector to A549 target cells.

Figure 2 Cell-based ADCC assay of 12G3H11 (anti-EphA2 antibody) and its I332E Fc variant using 50: 1 ratio of effector to A549 target cells.


Specifications

  • Host Species
  • Human
  • Derivation
  • Humanized
  • Type
  • Humanized IgG
  • Specificity
  • Human ITGAV
  • Species Reactivity
  • Human
  • Clone
  • 12G3
  • Applications
  • ADCC
  • Related Disease
  • Cancer

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The ITGAV antibody has been reported in applications of Antibody-dependent Cell-mediated Cytotoxicity.

Target

  • Alternative Names
  • Integrin Subunit Alpha V

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 12G3"

See other products for "ITGAV"

Human Antibody

CAT Product Name Application Type
TAB-076 Anti-Human CD51 Recombinant Antibody (Intetumumab) ELISA, FC, IP, FuncS, IF, Neut, ICC IgG1 - kappa

Humanized Antibody

CAT Product Name Application Type
TAB-H01 Anti-Human ITGAV Recombinant Antibody (Abituzumab) Inhib, Agonist IgG2 - kappa

Blocking Antibody

CAT Product Name Application Type
NEUT-1537CQ Recombinant Mouse Anti-ITGAV Antibody (272-17E6) Inhib, ICC/IF, BL, FC, ELISA, IP IgG1
NEUT-1577CQ Recombinant Mouse Anti-ITGAV Antibody (13C2) FC, IHC-Fr, ICC, IP, ELISA, Depletion, BL, Adhesion IgG1, κ
NEUT-1578CQ Recombinant Mouse Anti-ITGAV Antibody (NKI-M9) FC, IF, ELISA, BL, IP IgG2a, κ
NEUT-1580CQ Recombinant Mouse Anti-ITGAV Antibody (27.1) ICC/IF, FC, IP, IHC-Fr, BL IgG1
NEUT-1581CQ Recombinant Mouse Anti-ITGAV Antibody (P5H9) CyTOF, BL, FC, IP, ICC IgG1

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1582CQ Recombinant Rat Anti-Itgav Antibody (RMV-7) FC, FuncS, IP, Neut IgG1, κ

Rabbit Monoclonal Antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-076 Afuco™ Anti-ITGAV ADCC Recombinant Antibody (Intetumumab), ADCC Enhanced ELISA, FC, IP, FuncS, IF, Neut ADCC enhanced antibody
AFC-TAB-H01 Afuco™ Anti-ITGAV ADCC Recombinant Antibody (Abituzumab), ADCC Enhanced ELISA, IP, FC, FuncS, IF, Neut ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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