Human Anti-CD74 Recombinant Antibody (TAB-0571CL)
CAT#: TAB-0571CL
This product is a recombinant human antibody that recognizes CD74 (Cluster of Differentiation 74). The antibody was expressed in mammalian cells with chemically defined culture media and was purified by affinity chromatography.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human spleen
Immunohistochemical staining of human spleen shows strong granular cytoplasmic positivity.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10592/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IHC staining of human tonsil
Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in germinal center cells and non-germinal center cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79994/170659_A_6_8_selected.jpg
Subcellular Location and Protein Expression
Figure 4 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/203_F11_1_blue_red_green.jpg
Normal Tissue
Figure 5 Colon
Mucosal lymphoid cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/6593_A_7_3.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/6593_A_8_5.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/6593_A_8_8.jpg
Normal Tissue
Figure 8 Tonsil
Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/6593_A_6_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (CAPAN-2, Daudi, HDLM-2, REH, RPMI-8226, U-266/70, U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000019582-CD74
❮
❯
Specifications
- Immunogen
- TC2013-CD74
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human CD74 (Cluster of Differentiation 74)
- Species Reactivity
- Human
- Applications
- ELISA, FC
- Related Disease
- Autoimmune disease
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- See the COA
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CD74; CD74 molecule, major histocompatibility complex, class II invariant chain; II; DHLAG; HLADG; Ia-GAMMA; HLA class II histocompatibility antigen gamma chain; p33; HLA-DR-gamma; MHC HLA-DR gamma chain; Ia-associated invariant chain; gamma chain of class II antigens; HLA-DR antigens-associated invariant chain; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
- Gene ID
- 972
- UniProt ID
- P04233
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for TAB-0571CL. Click the button above to contact us or submit your feedback about this product.
Clear and Detailed Datasheets
The datasheet covers everything from dilutions to recommended blocking conditions. It's been very helpful for my workflow.
Fantastic in Various Applications
I've used this antibody for Western blot and ELISA. It performed well in both settings with minimal background noise.
Minimal Non-Specific Binding
Blocking and washing conditions recommended by the supplier work well. I encountered minimal non-specific bindings.
Q&As
-
Can antibodies be kept in buffer solutions?
A: Indeed, glycerol or BSA-containing buffer solutions are commonly used to store antibodies. Examine the specific recommendations provided by the provider.
-
How long can the antibody be stable at room temperature?
A: Antibodies should not be stored at room temperature for extended periods of time. Short handling-between thirty and sixty minutes-is frequently permitted.
-
Is it required to include a preservative in the antibody solution?
A: To stop microbiological growth, preservatives like sodium azide can be employed; just make sure they work well with the particular antibody application you're using.
View the frequently asked questions answered by Creative Biolabs Support.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "CD74"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-466-VHH | Recombinant Anti-Human CD74 VHH Single Domain Antibody | FUNC, FA, IP, ChiP | Llama VHH |
| TAB-0004CL-VHH | Anti-Human CD74 VHH Single Domain Antibody (TAB-0004CL-VHH) | ELISA, FC, Internalization, Inhib, FuncS | VHH |
| TAB-0005CL-VHH | Anti-Human CD74 VHH Single Domain Antibody (TAB-0005CL-VHH) | ELISA, FC, Internalization, Inhib, FuncS | VHH |
| TAB-0006CL-VHH | Anti-Human CD74 VHH Single Domain Antibody (TAB-0006CL-VHH) | ELISA, FC, Internalization, Inhib, FuncS | VHH |
| TAB-0007CL-VHH | Anti-Human CD74 VHH Single Domain Antibody (TAB-0007CL-VHH) | ELISA, FC, Internalization, Inhib, FuncS | VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0569CL-S(P) | Human Anti-CD74 Recombinant Antibody; scFv Fragment (TAB-0569CL-S(P)) | ELISA, FC | Human scFv |
| TAB-0570CL-S(P) | Human Anti-CD74 Recombinant Antibody; scFv Fragment (TAB-0570CL-S(P)) | ELISA, FC | Human scFv |
| TAB-0571CL-S(P) | Human Anti-CD74 Recombinant Antibody; scFv Fragment (TAB-0571CL-S(P)) | ELISA, FC | Human scFv |
| TAB-0572CL-S(P) | Human Anti-CD74 Recombinant Antibody; scFv Fragment (TAB-0572CL-S(P)) | ELISA, FC | Human scFv |
| TAB-0573CL-S(P) | Human Anti-CD74 Recombinant Antibody; scFv Fragment (TAB-0573CL-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-408CQ | Mouse Anti-CD74 Recombinant Antibody (clone LN2) | FC, IHC-Fr, IHC-P, ICC, IP, WB, Block | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0579 | Hi-Affi™ Rabbit Anti-CD74 Recombinant Antibody (clone DS579AB) | ICC, IHC-P, IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0388-FY-S(P) | Human Anti-CD74 Recombinant Antibody; scFv Fragment (HPAB-0388-FY-S(P)) | FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0388-FY-F(E) | Human Anti-CD74 Recombinant Antibody; Fab Fragment (HPAB-0388-FY-F(E)) | FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-XY404 | Mouse Anti-CD74 Recombinant Antibody (clone 2D1B11) | ELISA, WB, FC | Mouse IgG1 |
| VS3-XY405 | Mouse Anti-CD74 Recombinant Antibody (clone 2D1B3) | ELISA, WB, FC | Mouse IgG1 |
| VS3-XY406 | Mouse Anti-CD74 Recombinant Antibody, FITC (clone 4ALN2) | FC, IF | Mouse IgG1 |
| VS3-XY407 | Mouse Anti-CD74 Recombinant Antibody, PE (clone 4ALN2) | FC, IHC, IP, IF, WB | Mouse IgG1 |
| VS3-XY408 | Mouse Anti-CD74 Recombinant Antibody (clone 4ALN2) | FC, IHC, IP, IF, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY55 | AbPlus™ Anti-CD74 Magnetic Beads (4ALN2) | IP, Protein Purification | |
| VS-0724-YC321 | AbPlus™ Anti-CD74 Magnetic Beads (VS-0724-YC321) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY110 | Mouse Anti-NHP CD74 Recombinant Antibody (clone LN-2) | WB, IHC, IF, FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY71 | CytoStream™ Mouse Anti-CD74 Recombinant Antibody (clone LN2) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY83 | Human Anti-CD74 (clone LL1) scFv-Fc Chimera | FC, ELISA, Cyt | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC330 | Recombinant Anti-CD74 Vesicular Antibody, EV Displayed (VS-0425-YC330) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1217 | Anti-CD74 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1218 | Anti-Mouse CD74 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
-2.png)
Application: IB, ELISA, FC, FuncS
Application: FC, IB, Block, Inhib, FuncS, ELISA, FACS, IP, IF
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, IHC, FC, IP, IF, BL
Application: ELISA, FuncS
Application: ELISA, FC, Neut, Inhib
-4.jpg)
Application: FC
Application: ELISA, Cyt, PP, Inhib
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
