Mouse Anti-NHP CD74 Recombinant Antibody (clone LN-2)

Name: Mouse Anti-NHP CD74 Recombinant Antibody (clone LN-2)
SKU: VS-1024-XY110
Rating: 5 (1 reviews)

CAT#: VS-1024-XY110

The monoclonal antibody of mouse origin is engineered to specifically bind to CD74, exhibiting reactivity across human, mouse, and non-human primate species. It is extensively validated for use in Western blot (WB), immunohistochemistry (IHC), immunofluorescence (IF), and flow cytometry (FC), making it a highly versatile tool. Designed to provide precise and reliable results, this antibody is a valuable resource for researchers seeking to elucidate the role of CD74 in various biological contexts and across diverse applications.

Gene Expression

Subcellular Location and Protein Expression Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/if_selected.jpg

Subcellular Location and Protein Expression Figure 2 IHC staining of human spleen

Immunohistochemical staining of human spleen shows strong granular cytoplasmic positivity.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10592/ihc_selected.jpg

Subcellular Location and Protein Expression Figure 3 IHC staining of human tonsil

Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in germinal center cells and non-germinal center cells.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79994/170659_A_6_8_selected.jpg

Subcellular Location and Protein Expression Figure 4 IF staining of human cell line U-251 MG

Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/203_F11_1_blue_red_green.jpg

Normal Tissue Figure 5 Colon

Mucosal lymphoid cells
Staining:High
Intensity: Strong
Quantity: 75%-25%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/6593_A_7_3.jpg

Normal Tissue Figure 6 Kidney

Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/6593_A_8_5.jpg

Normal Tissue Figure 7 Lymph node

Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/6593_A_8_8.jpg

Normal Tissue Figure 8 Tonsil

Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/6593_A_6_8.jpg

RNA Expression Figure 9 RNA cell line category: Cell line enhanced (CAPAN-2, Daudi, HDLM-2, REH, RPMI-8226, U-266/70, U-698)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000019582-CD74

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Specifications

Immunogen
SU-DHL-4 lymphoma cells

Host Species
Mouse

Type
Mouse IgG1, kappa

Specificity
CD74

Species Reactivity
Non-human primate, Human, Mouse

Clone
LN-2

Applications
WB, IHC, IF, FC

Product Property

Purification
Protein A purified

Purity
>95%, determined by SDS-PAGE

Format
Liquid

Buffer
PBS, pH 7.4, with 0.05% BSA

Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Applications

Application Notes
WB: 2-4 µg/mL, IHC: 1-2 µg/mL, IF: 2-3 µg/mL, FC: 1-2 µg/10⁶ cells

Target

Alternative Names
II; p33; CLIP; DHLAG; HLADG; Ia-GAMMA;

Gene ID
972

UniProt ID
P04233

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - VS-1024-XY110.pdf

MSDS

MSDS - VS-1024-XY110.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Protocol & Troubleshooting

Immunofluorescence (IF)

Immunohistochemistry (IHC)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

Recommended Dilution Buffer

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Product Name

Isotype Control

CAT
Product Name

Secondary Antibody

CAT
Product Name

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MHC-LC2820	PE-H2-IAb/Human CD74 (KPVSKMRMATPLLMQAL) MHC Tetramer	FCM
MHC-LC2821	PE-H2-IAd/Human CD74 (KPVSKMRMATPLLMQAL) MHC Tetramer	FCM
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NEUT-408CQ	Mouse Anti-CD74 Recombinant Antibody (clone LN2)	FC, IHC-Fr, IHC-P, ICC, IP, WB, Block	Mouse IgG1, κ

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