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    Anti-Mouse CSF1R Recombinant Antibody (AFS98) (CAT#: TAB-079MZ)

    Recombinant monoclonal antibody to CSF-1R, AFS98, is a rat monoclonal antibody intended for the prophylaxis and treatment of related disease.

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Published Data
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    FC

    Figure 1 Representative dot plots and quantification of the F4/80+ Ly6C-  and CSF1R+ of F4/80+ immune cell infiltrates of WT and Csf1–/– MC38 tumors derived from WT mice at day 21.

    Figure 1 Representative dot plots and quantification of the F4/80+ Ly6C-  and CSF1R+ of F4/80+ immune cell infiltrates of WT and Csf1–/– MC38 tumors derived from WT mice at day 21.

    Graphs show mean ± SEM of data from at least 3 independent experiments or 5 to 10 individual mice per group.

    Gyori, D., Lim, E. L., Grant, F. M., Spensberger, D., Roychoudhuri, R., Shuttleworth, S. J., ... & Hawkins, P. T. (2018). Compensation between CSF1R+ macrophages and Foxp3+ Treg cells drives resistance to tumor immunotherapy. JCI insight, 3(11).


    Specifications

    • Host Species
    • Rat
    • Specificity
    • Mouse
    • Clone
    • AFS98
    • Applications
    • FC

    Applications

    • Application Notes
    • The CSF1R antibody has been reported in applications of Flow Cytometry. TAMs were isolated from other leukocytes by positive selection for CD115 (anti-mouse CD115-PE, clone AFS98, Biolegend) used at a 1:200 dilution in FACS buffer and incubated at 4°C for 30 minutes. After washing, the cells were incubated with anti-PE microbeads (Miltenyi Biotec) at a 1:10 dilution in FACS buffer at 4°C for a further 20 minutes.

    Target

    • Alternative Names
    • Fms; Fim2; CD115; Csfmr; Fim-2; CSF-1R; M-CSFR; M-CSF-R; AI323359

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

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    Please select product type
    ADCC Enhanced Antibodies Fab Antibodies Mouse Antibodies Humanized Antibodies Neutralizing Antibodies Rabbit Monoclonal Antibodies IgG Antibodies ScFv Antibodies ScFv-Fc Chimeras Extracellular Vesicle Antibodies IHC Kits & Antibodies
    CAT Product Name Application Type
    AFC-178CL Afuco™ Anti-CSF1R Recombinant Antibody (AFC-178CL), ADCC Enhanced ELISA, WB Human IgG1
    AFC-TAB-H23 Afuco™ Anti-CSF1R ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H23) ELISA, IP, FC, FuncS, Neut ADCC enhanced antibody
    AFC-TAB-011ML Afuco™ Anti-CSF1R ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-011ML) ELISA, IHC, FC, IP, IF, Inhib ADCC enhanced antibody

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    For Research Use Only. Not For Clinical Use.

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