Anti-Mouse CSF1R Recombinant Antibody (AFS98) (CAT#: TAB-079MZ)
Recombinant monoclonal antibody to CSF-1R, AFS98, is a rat monoclonal antibody intended for the prophylaxis and treatment of related disease.
Specific Inquiry
FC
Figure 1 Representative dot plots and quantification of the F4/80+ Ly6C- and CSF1R+ of F4/80+ immune cell infiltrates of WT and Csf1–/– MC38 tumors derived from WT mice at day 21.
Graphs show mean ± SEM of data from at least 3 independent experiments or 5 to 10 individual mice per group.
Gyori, D., Lim, E. L., Grant, F. M., Spensberger, D., Roychoudhuri, R., Shuttleworth, S. J., ... & Hawkins, P. T. (2018). Compensation between CSF1R+ macrophages and Foxp3+ Treg cells drives resistance to tumor immunotherapy. JCI insight, 3(11).
Specifications
- Host Species
- Rat
- Specificity
- Mouse
- Clone
- AFS98
- Applications
- FC
Applications
- Application Notes
- The CSF1R antibody has been reported in applications of Flow Cytometry. TAMs were isolated from other leukocytes by positive selection for CD115 (anti-mouse CD115-PE, clone AFS98, Biolegend) used at a 1:200 dilution in FACS buffer and incubated at 4°C for 30 minutes. After washing, the cells were incubated with anti-PE microbeads (Miltenyi Biotec) at a 1:10 dilution in FACS buffer at 4°C for a further 20 minutes.
Target
- Alternative Names
- Fms; Fim2; CD115; Csfmr; Fim-2; CSF-1R; M-CSFR; M-CSF-R; AI323359
- Gene ID
- 12978
- UniProt ID
- P09581
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H23 | Anti-Human CSF1R Recombinant Antibody (Emactuzumab) | WB, ELISA, IP, FC, FuncS, Neut, IF | IgG1 - kappa |
| TAB-076MZ | Human Anti-CSF1R Recombinant Antibody (TAB-076MZ) | WB | Human IgG4 |
| TAB-078MZ | Human Anti-CSF1R Recombinant Antibody (TAB-078MZ) | ELISA | Humanized IgG |
| TAB-076MZ-S(P) | Human Anti-CSF1R Recombinant Antibody; scFv Fragment (TAB-076MZ-S(P)) | WB | Human scFv |
| TAB-078MZ-S(P) | Human Anti-CSF1R Recombinant Antibody; scFv Fragment (TAB-078MZ-S(P)) | ELISA | Humanized scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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