Anti-CSF1R Recombinant Antibody Products

Creative Biolabs is committed to accelerating the research and discovery of the target CSF1R by providing recombinant products that exemplify the highest quality standards. Our offerings not only deliver exceptional value but also come with top-notch technical support to ensure researchers can effectively utilize our products in their studies. By focusing on CSF1R, we aim to empower scientists in their efforts to explore this critical target, ultimately contributing to advancements in understanding and treating related diseases.

CSF1R: A Potential Therapeutic Target in Autoimmune Diseases and Cancer

The target CSF1R (colony-stimulating factor 1 receptor) is a crucial protein in biological systems. CSF1R is mainly involved in regulating the survival, proliferation, and differentiation of cells such as macrophages. Research on CSF1R is of great significance. It can help us understand the mechanisms of immune responses and inflammatory processes. By targeting CSF1R, scientists can develop new therapeutic strategies for diseases related to abnormal macrophage activation, such as certain autoimmune diseases and cancer. Studying CSF1R also provides insights into the development and function of the immune system, potentially leading to the discovery of novel treatments for a variety of disorders.

Alternative Names

Colony stimulating factor 1 receptor; FMS; CSFR; FIM2; GPSC; HDLS; C-FMS; CD115; HDLS1; CSF-1R; BANDDOS; M-CSF-R

Background

The protein encoded by this gene is the receptor for colony-stimulating factor 1, a cytokine that controls the production, differentiation, and function of macrophages. This receptor mediates most if not all the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and a member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines, and anaplastic large cell lymphoma.

Anti-CSF1R rAb Products

We provide high-quality and excellent antibody products to fulfill the research needs of a diverse group of researchers about the target CSF1R and its functions.

Creative Quality Control

To satisfy our customers' requirements, we have instituted a set of stringent quality management systems throughout the production process of antibody products to guarantee their high quality.

Customer Reviews

Excellent

D**e
Anti-Human CSF1R Recombinant Antibody (Emactuzumab) (Cat#: TAB-H23)

The anti-human CSF1R recombinant antibody has proven to be highly beneficial for my research endeavors. I employed it in ELISA and IF assays to examine CSF1R expression in particular cell types and tissues. In the ELISA assay, it delivered precise and consistent results, enabling me to determine the amount of CSF1R present. The IF experiments vividly showed the location of CSF1R within cells. This antibody has been an essential instrument in my investigations of the function of CSF1R in different biological settings and has assisted me in obtaining a crucial understanding of associated diseases.

18/Feb/2022

Excellent

Wi**ams
Anti-Human CSF1R Recombinant Antibody (Cabiralizumab) (Cat#: TAB-011ML)

This antibody has been extremely useful for my research. In IHC and FC assays, I employed it to analyze CSF1R expression in specific tissues and cell types. Through IHC, it offered distinct staining and precise localization of CSF1R. With FC, it enabled accurate quantification and characterization of CSF1R-positive cells. The results were highly dependable and have greatly contributed to my understanding of CSF1R's function in particular biological scenarios. I would highly recommend this antibody to fellow researchers.

14/Nov/2023

Excellent

F**na
Anti-Human CSF1R Recombinant Antibody (Emactuzumab) (Cat#: TAB-H23)

I used this antibody in cell-based assays to detect CSF1R expression in certain tumor cell lines. The results were excellent, providing clear signals and allowing me to study the role of CSF1R in tumor progression. This antibody has significantly contributed to my understanding of the molecular mechanisms involved and has opened up new avenues for potential therapeutic interventions.

15/Aug/2022

rAb Production

Creative Biolabs provides one-stop services covering everything from gene synthesis to the production of high-quality recombinant antibodies. As a result, we can offer customers excellent antibody production services.

Featured Anti-CSF1R Recombinant Antibody Production Platforms
Fig.6 Milligram-scale recombinant antibody production.

Fig.7 Gram-scale recombinant antibody production.

rAb Modalities

Creative Biolabs is dedicated to supplying researchers with a wide range of high-quality recombinant antibodies in diverse formats that are both comprehensive and state-of-the-art. This enables researchers to meet their various research requirements and saves them time and effort.

Fig.8 Full Length Anti-CSF1R Recombinant Antibody Production and Modalities.

Drug Information Targeting CSF1R

Table 1. Therapeutic approaches targeting CSF1R in clinical development.

If you need more detailed information on anti-CSF1R recombinant antibody products, please don't hesitate to contact us. Our team is enthusiastic about providing the assistance you need and is eager to establish a beneficial and productive partnership that advances your research goals.