This antibody specifically binding to chemokine receptor CXCR2 may be used for treatment of diseases involving aberrant functioning of CXCR2.
Figure 1 Inhibition of FLAG-tagged nanobody binding to CHO-CXCR2 cells by monovalent nanobodies using FLAG-tagged 163E3 and using FLAG-tagged 127D1.
Competition experiments using a representative FLAGtagged monovalent nanobody from each class (127D1 for class 1 and 163E3 for class 2) showed that nanobodies within the same class compete with each other, whereas nanobodies from different classes do not compete with each other.
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