Human Anti-DDR1 Recombinant Antibody (clone APE05570); Fab Fragment (CAT#: HPAB-0077-CN-F(E))
An anti-DDR1 antibody which binds to DDR1 comprises the immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. This antibody can be used to treat a DDR1-mediated disease such as renal disease.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57194/if_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57194/if_selected.jpg
Figure 2 Lymph node
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_A_9_8.jpg
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_A_9_8.jpg
Figure 3 Cerebral cortex
(Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_B_7_5.jpg
(Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_B_7_5.jpg
Figure 4 Kidney
(Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_A_8_5.jpg
(Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_A_8_5.jpg
Figure 5 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_A_5_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_A_5_6.jpg
Figure 6 Skin
(Melanocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_B_7_1.jpg
(Melanocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_B_7_1.jpg
Figure 7 RNA cell line category: Cell line enhanced (HaCaT, HBEC3-KT, RT4, T-47d)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000204580-DDR1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000204580-DDR1
Specifications
- Host Species
- Human
- Derivation
- IgG evolvable library
- Type
- Human Fab
- Specificity
- Human DDR1
- Species Reactivity
- Human, Mouse
- Clone
- APE05570
- Applications
- ELISA, FC
- Related Disease
- DDR1-mediated disease such as renal disease
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Discoidin Domain Receptor Tyrosine Kinase 1; CD167 Antigen-Like Family Member A; Protein-Tyrosine Kinase RTK-6; Mammary Carcinoma Kinase 10; Tyrosine-Protein Kinase CAK; Cell Adhesion Kinase; Tyrosine Kinase DDR; EC 2.7.10.1; EDDR1; NTRK4; PTK3A; HGK2; RTK6; TRKE; CAK; NEP; Neurotrophic Tyrosine Kinase, Receptor, Type 4; Discoidin Domain Receptor Family, Member 1; Epithelial Discoidin Domain Receptor 1; Discoidin Receptor Tyrosine Kinase; PTK3A Protein Tyrosine Kinase 3A; Neuroepithelial Tyrosine Kinase; Protein-Tyrosine Kinase 3A; CD167a Antigen; EC 2.7.10; MCK-10; CD167; MCK10; TRK E; PTK3; DDR
- Gene ID
- 780
- UniProt ID
- Q08345
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-433 | Mouse Anti-DDR1 Recombinant Antibody (clone 3E3); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0061-LSX-F(E) | Mouse Anti-DDR1 Recombinant Antibody (clone AB2026); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0062-LSX-F(E) | Mouse Anti-DDR1 Recombinant Antibody (clone AB2039); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0063-LSX-F(E) | Mouse Anti-DDR1 Recombinant Antibody (clone AB2031); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0064-LSX-F(E) | Mouse Anti-DDR1 Recombinant Antibody (clone AB2074); Fab Fragment | ELISA | Mouse Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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