Mouse Anti-DDR1 Recombinant Antibody (clone 3E3); Fab Fragment
CAT#: PFBL-433
Recombinant Mouse Antibody (3E3) Fab Fragment is specific to DDR1, expressed in Chinese Hamster Ovary cells (CHO). This Fab fragment uses predominantly aromatic residues to recognize this epitope: Thr30, Phe32, Tyr34, Tyr49, and Leu50 of the light chain; and Ile31, Trp33, Tyr52, Tyr56, and Tyr96 of the heavy chain.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & cell junctions.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/57194/if_selected.jpg
Normal Tissue
Figure 2 Lymph node
Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_A_9_8.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_B_7_5.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_A_5_6.jpg
Normal Tissue
Figure 6 Skin
Melanocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_B_7_1.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (HaCaT, HBEC3-KT, RT4, T-47d)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000204580-DDR1
❮
❯
Specifications
- Immunogen
- Human discoidin domain receptor tyrosine kinase 1
- Host Species
- Mouse
- Type
- Mouse Fab
- Specificity
- Human DDR1
- Species Reactivity
- Human
- Clone
- 3E3
- Applications
- ELISA, FC
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- DDR1; discoidin domain receptor tyrosine kinase 1; CAK; DDR; NEP; HGK2; PTK3; RTK6; TRKE; CD167; EDDR1; MCK10; NTRK4; PTK3A; epithelial discoidin domain-containing receptor 1; tyrosine kinase DDR; cell adhesion kinase; mammary carcinoma kinase 10; tyrosine-protein kinase CAK; protein-tyrosine kinase RTK-6; neuroepithelial tyrosine kinase; PTK3A protein tyrosine kinase 3A; CD167 antigen-like family member A; neurotrophic tyrosine kinase, receptor, type 4
- Gene ID
- 780
- UniProt ID
- Q08345
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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- CAT
- Product Name
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| CAT | Product Name | Application | Type |
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| TAB-177MZ-F(E) | Anti-Human DDR1 Recombinant Antibody Fab Fragment (DDR1-ab2) | IF | Human antibody |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1224CT | Recombinant Mouse anti-Human DDR1 Monoclonal antibody (3H5F23) | ELISA, IHC-P, WB | |
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| CAT | Product Name | Application | Type |
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| HPAB-0077-CN-F(E) | Human Anti-DDR1 Recombinant Antibody (clone APE05570); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-0078-CN-F(E) | Human Anti-DDR1 Recombinant Antibody (clone APE05571); Fab Fragment | ELISA, FC | Human Fab |
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