Recombinant Mouse Anti-HRV14 VP1 Antibody (17-IA) (CAT#: PABW-074)

Recombinant Mouse Antibody (17-IA) is capable of binding to HRV14 VP1, expressed in Chinese Hamster Ovary cells (CHO). 17-IA binds to the NIm-IA site,which was defined by natural escape mutations at residues D1091 and E1095 of VP1 β-barrel.


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Neut

Figure 1 Fab12 and Fab17 neutralization and precipitation properties.

Figure 1 Fab12 and Fab17 neutralization and precipitation properties.

(A) The abilities of MAb12 and MAb17 to inhibit plaque formation were measured (method A) at various antibody concentrations. (B) The abilities of the antibodies MAb12 and MAb17 to precipitate the virions were measured over a comparable range of antibody concentrations.

Che, Z., Olson, N. H., Leippe, D., Lee, W. M., Mosser, A. G., Rueckert, R. R., ... & Smith, T. J. (1998). Antibody-mediated neutralization of human rhinovirus 14 explored by means of cryoelectron microscopy and X-ray crystallography of virus-Fab complexes. Journal of virology, 72(6), 4610-4622.


Specifications

  • Immunogen
  • HRV14 Major capsid protein VP1
  • Host Species
  • Mouse
  • Derivation
  • Mouse
  • Type
  • IgG
  • Specificity
  • Tested positive against native HRV14 VP1
  • Species Reactivity
  • HRV14
  • Clone
  • 17-IA
  • Applications
  • Can be useful in applications such as: Neutralization

Product Property

  • Purity
  • >95% by SDS-PAGE and HPLC analysis
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Target

  • Alternative Names
  • Major capsid protein VP1; VP1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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Single-domain Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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