Recombinant Mouse Anti-Hemagglutinin (HA) Antibody (S139/1) (CAT#: PABX-069)
Anti-Hemagglutinin (HA) antibody is a Mouse antibody of IgG class that binds to an Hemagglutinin (HA). This antibody binds the globular head of a single Vic75/H3 HA protomer at and around the receptor binding site.
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Neut
Figure 1 Neutralizing activity of MAb S139/1 to PR8 mutants with altered epitopes.
Yoshida, R., Igarashi, M., Ozaki, H., Kishida, N., Tomabechi, D., Kida, H., ... & Takada, A. (2009). Cross-protective potential of a novel monoclonal antibody directed against antigenic site B of the hemagglutinin of influenza A viruses. PLoS pathogens, 5(3).
Neut
Figure 2 Neutralization activity of MAb S139/1 to various HA subtypes of influenza A virus strains.
Viruses were mixed with indicated concentrations of the purified MAb S139/1. Neutralization activities were evaluated by plaque reduction assays using MDCK cells.
Yoshida, R., Igarashi, M., Ozaki, H., Kishida, N., Tomabechi, D., Kida, H., ... & Takada, A. (2009). Cross-protective potential of a novel monoclonal antibody directed against antigenic site B of the hemagglutinin of influenza A viruses. PLoS pathogens, 5(3).
FuncS
Figure 3 Protective efficacy of passive immunization with MAb S139/1 in mice.
Yoshida, R., Igarashi, M., Ozaki, H., Kishida, N., Tomabechi, D., Kida, H., ... & Takada, A. (2009). Cross-protective potential of a novel monoclonal antibody directed against antigenic site B of the hemagglutinin of influenza A viruses. PLoS pathogens, 5(3).
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- IgG
- Specificity
- Tested positive against native Influenza a virus Hemagglutinin (HA)
- Species Reactivity
- Influenza a virus
- Clone
- S139/1
- Applications
- Neut, FuncS
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- This antibody has been reported for use in Functional Assay and Neutralization. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. should be carefully titrated in specific assays.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Single Domain Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-223 | Recombinant Human Anti-IAV HA1 chain Antibody (C05) | WB, ELISA, FuncS | IgG |
| PABL-224 | Recombinant Human Anti-IAV HA1 chain Antibody (F045-092) | WB, ELISA, FuncS | IgG |
| PABC-160 | Human Anti-HA Recombinant Antibody (PABC-160) | Neut, ELISA, FC | Human IgG |
| PABC-233 | Recombinant Human Anti-H3N2 HA Antibody (F045-092) | Neut | IgG |
| MOB-223CQ | Mouse Anti-HA Recombinant Antibody (clone 16B12) | ELISA, IHC | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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