Anti-human IL21R Recombinant Antibody (MUF) (TAB-588LC)
CAT#: TAB-588LC
It is a recombinant antibody targeting the human interleukin-21 receptor (IL-21R), derived from human. It has potent affinity against IL-21R. This antibody can also be potentially used in the research of arthritis and transplant rejection. This product has been detected by Enzyme-linked immunosorbent assay, Flow cytometry and Blocking assay.
Published Data
Gene Expression
FC
Figure 1 The result of a binding assay analyzed by FACS which shows that both MUF and MU11 bind on the surface of human IL-21 R.
FC
Figure 2 The result of a binding assay analyzed by FACS which shows that MUF binds IL-21 R on mouse B cells.
ELISA
Figure 3 The result of an ELISA which shows that MUF inhibits the binding of human IL-21 to human IL-21 R.
Block
Figure 4 The result of a cell-proliferation assay which shows that addition of MUF blocked the ability of IL-21 to increase the proliferation of human CD4+ T cells.
Block
Figure 5 The result of a cell-proliferation assay which shows that both MUF scFv and MUF IgG blocked the ability of IL-21 to increase the proliferation of Baf3Mu-1 cells which express an IL-21 R.
❮
❯
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/if_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_A_8_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_A_6_6.jpg
Normal Tissue
Figure 6 Bone marrow
Hematopoietic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_B_6_4.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (Daudi, HDLM-2, Karpas-707, RH-30, RPMI-8226, U-266/70)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000103522-IL21R
❮
❯
Specifications
- Host Species
- Human
- Derivation
- Antibody phagemid library
- Type
- Human antibody
- Specificity
- Human
- Clone
- MUF
- Applications
- ELISA, FC, Block
- Related Disease
- Arthritis and transplant rejection
Applications
- Application Notes
- This antibody has been tested for use in Flow Cytometry, Enzyme-Linked Immunosorbent Assay and Blocking.
Target
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for TAB-588LC. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone MUF"
- CAT
- Product Name
See other products for "IL21R"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-583LC | Rat Anti-IL21R Recombinant Antibody (TAB-583LC) | ELISA, WB | Rat IgG |
| TAB-584LC | Rat Anti-IL21R Recombinant Antibody (TAB-584LC) | ELISA, WB | Rat IgG |
| TAB-583LC-S(P) | Rat Anti-IL21R Recombinant Antibody; scFv Fragment (TAB-583LC-S(P)) | ELISA, WB | Rat scFv |
| TAB-584LC-S(P) | Rat Anti-IL21R Recombinant Antibody; scFv Fragment (TAB-584LC-S(P)) | ELISA, WB | Rat scFv |
| TAB-583LC-F(E) | Rat Anti-IL21R Recombinant Antibody; Fab Fragment (TAB-583LC-F(E)) | ELISA, WB | Rat Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-585LC | Human Anti-IL21R Recombinant Antibody (TAB-585LC) | ELISA, FC | Human IgG2, κ |
| TAB-586LC | Human Anti-IL21R Recombinant Antibody (TAB-586LC) | ELISA, FC | Human IgG2, κ |
| TAB-587LC | Human Anti-IL21R Recombinant Antibody (TAB-587LC) | ELISA, FC | Human IgG2, κ |
| TAB-589LC | Anti-human IL21R Recombinant Antibody (MU11) (TAB-589LC) | ELISA, FC, Block | Human antibody |
| TAB-590LC | Anti-human IL21R Recombinant Antibody (18G4) (TAB-590LC) | ELISA, FC | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0965CT | Recombinant Mouse anti-Human IL21R Monoclonal antibody (NN0406-0A37) | WB | |
| HPAB-0247CQ | Human Anti-IL21R Recombinant Antibody (clone 19F5) | Neut, WB, ELISA, FC, IHC | Human IgG1 |
| FAMAB-1203CQ | Human Anti-IL21R Recombinant Antibody (clone ATR-107) | Inhib, FC, WB | Human IgG1 |
| VS3-FY279 | Recombinant Mouse Anti-IL21R Antibody (clone 1C3B12) | ELISA, FC | Mouse IgG1 |
| VS3-FY280 | Recombinant Mouse Anti-IL21R Antibody (clone 1C3G9) | ELISA, ICC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1327CQ | Rat Anti-Il21r Recombinant Antibody (VMC196) | Block | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4261 | Rabbit Anti-IL21R Recombinant Antibody (clone SI341DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0668-CN-S(P) | Human Anti-IL21R Recombinant Antibody (clone 18A5); scFv Fragment | ELISA, FC, Neut | Human scFv |
| HPAB-0669-CN-S(P) | Human Anti-IL21R Recombinant Antibody (clone ABS); scFv Fragment | ELISA, FC, Neut | Human scFv |
| HPAB-0247CQ-S(P) | Human Anti-IL21R Recombinant Antibody (clone 19F5); scFv Fragment | ELISA, FC, Inhib | Human scFv |
| HPAB-AP685-YC-S(P) | Human Anti-IL21R Recombinant Antibody (clone C2); scFv Fragment | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0668-CN-F(E) | Human Anti-IL21R Recombinant Antibody (clone 18A5); Fab Fragment | ELISA, FC, Neut | Human Fab |
| HPAB-0669-CN-F(E) | Human Anti-IL21R Recombinant Antibody (clone ABS); Fab Fragment | ELISA, FC, Neut | Human Fab |
| HPAB-0247CQ-F(E) | Human Anti-IL21R Recombinant Antibody (clone 19F5); Fab Fragment | ELISA, FC, Inhib | Human Fab |
| HPAB-AP685-YC-F(E) | Human Anti-IL21R Recombinant Antibody (clone C2); Fab Fragment | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY133 | CytoStream™ Mouse Anti-IL21R Recombinant Antibody (VS-0225-XY133) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC547 | Recombinant Anti-IL21R Vesicular Antibody, EV Displayed (VS-0425-YC547) | ELISA, FC, Neut, Cell-uptake |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: WB, ELISA, IP, FC, FuncS, Neut, IF
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
-2.png)
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, WB
Application: ELISA, WB, Neut, Funcs, IHC, Inhib
Application: Neut, ELISA, FuncS
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, FC, IF, IHC, WB
Application: FC
Application: ELISA, FC, WB, Inhib, IHC
Application: ELISA, Activ, Block
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
