It is a recombinant antibody targeting the human interleukin-21 receptor (IL-21R), derived from human. It has potent affinity against IL-21R. This antibody can also be potentially used in the research of arthritis and transplant rejection. This product has been detected by Enzyme-linked immunosorbent assay, Flow cytometry and Blocking assay.
Figure 1 The result of a binding assay analyzed by FACS which shows that both MUF and MU11 bind on the surface of human IL-21 R.
Figure 2 The result of a binding assay analyzed by FACS which shows that MUF binds IL-21 R on mouse B cells.
Figure 3 The result of an ELISA which shows that MUF inhibits the binding of human IL-21 to human IL-21 R.
Figure 4 The result of a cell-proliferation assay which shows that addition of MUF blocked the ability of IL-21 to increase the proliferation of human CD4+ T cells.
Figure 5 The result of a cell-proliferation assay which shows that both MUF scFv and MUF IgG blocked the ability of IL-21 to increase the proliferation of Baf3Mu-1 cells which express an IL-21 R.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-583LC | Rat Anti-IL21R Recombinant Antibody (TAB-583LC) | ELISA, WB | Rat IgG |
TAB-583LC-S(P) | Rat Anti-IL21R Recombinant Antibody; scFv Fragment (TAB-583LC-S(P)) | ELISA, WB | Rat scFv |
TAB-584LC-S(P) | Rat Anti-IL21R Recombinant Antibody; scFv Fragment (TAB-584LC-S(P)) | ELISA, WB | Rat scFv |
TAB-583LC-F(E) | Rat Anti-IL21R Recombinant Antibody; Fab Fragment (TAB-583LC-F(E)) | ELISA, WB | Rat Fab |
TAB-584LC-F(E) | Rat Anti-IL21R Recombinant Antibody; Fab Fragment (TAB-584LC-F(E)) | ELISA, WB | Rat Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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