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IL21R

Anti-IL21R Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


IL21R encodes the receptor for IL-21, a cytokine that is important for the regulation of immune responses. IL-21 influences the differentiation and activation of various immune cells, including T cells, B cells, and NK cells. It plays a crucial role in the development of humoral immune responses and the regulation of autoimmune diseases. Mutations in IL21R can lead to immune deficiencies and an increased susceptibility to autoimmune conditions like lupus and rheumatoid arthritis.
Protein class

Cancer-related genes, CD markers, Disease related genes

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (T-cells, NK-cells, dendritic cells, B-cells, Plasma cells, Langerhans cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (Daudi, HDLM-2, Karpas-707, RH-30, RPMI-8226, U-266/70)

Interaction

Heterodimer with the common gamma subunit. Associates with JAK1.

Molecular function

Receptor

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