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IL21R

Tryptophan C-mannosylation is an unusual co-translational protein modification performed by metazoans and apicomplexan protists. The prevalence and biological function of this modification are poorly understood, and progress in the field has been hampered by a lack of convenient tools to install and monitor the modification.
Protein class

Cancer-related genes, CD markers, Disease related genes

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (T-cells, NK-cells, dendritic cells, B-cells, Plasma cells, Langerhans cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (Daudi, HDLM-2, Karpas-707, RH-30, RPMI-8226, U-266/70)

Interaction

Heterodimer with the common gamma subunit. Associates with JAK1.

Molecular function

Receptor

More Types Infomation
More Infomation

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For Research Use Only. Not For Clinical Use.

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