Anti-human IL21R Recombinant Antibody (MU11) (TAB-589LC) (CAT#: TAB-589LC)

Recombinant monoclonal antibody MU11 is a human monoclonal antibody that specifically binds to human IL-21R and can be potentially used in the treatment of arthritis and transplant rejection.

Specific Inquiry
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  • Purity:
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  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
ELISA

Figure 1 A depicts the result of an ELISA which shows that MU11 specifically bind to human IL-21 R.

Figure 1 A depicts the result of an ELISA which shows that MU11 specifically bind to human IL-21 R.

FC

Figure 2 The result of a binding assay analyzed by FACS which shows that both MUF and MU11 bind on the surface of human IL-21 R.

Figure 2 The result of a binding assay analyzed by FACS which shows that both MUF and MU11 bind on the surface of human IL-21 R.

ELISA

Figure 3 The result of an ELISA which shows that MUF inhibits the binding of human IL-21 to human IL-21 R.

Figure 3 The result of an ELISA which shows that MUF inhibits the binding of human IL-21 to human IL-21 R.

Block

Figure 4 The result of a cell-proliferation assay which shows that MU11 blocked the ability of IL-21 in COS cell culture media to increase the proliferation of mouse CD4+ T cells.

Figure 4 The result of a cell-proliferation assay which shows that MU11 blocked the ability of IL-21 in COS cell culture media to increase the proliferation of mouse CD4+ T cells.

Block

Figure 5 The result of a cell-proliferation assay which shows that MU11 blocked the ability of IL-21 in COS cell culture media to increase the proliferation of mouse CD8+ T cells, in a dose-dependent manner.

Figure 5 The result of a cell-proliferation assay which shows that MU11 blocked the ability of IL-21 in COS cell culture media to increase the proliferation of mouse CD8+ T cells, in a dose-dependent manner.


Specifications

  • Host Species
  • Human
  • Derivation
  • Antibody phagemid library
  • Type
  • Human antibody
  • Specificity
  • Human
  • Clone
  • MU11
  • Applications
  • ELISA, FC, Block
  • Related Disease
  • Arthritis and transplant rejection

Applications

  • Application Notes
  • This antibody has been tested for use in Flow Cytometry, Enzyme-Linked Immunosorbent Assay and Blocking.

Target

  • Alternative Names
  • IL21R; interleukin 21 receptor; NILR; CD360; interleukin-21 receptor; IL-21 receptor; novel interleukin receptor

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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