Recombinant monoclonal antibody MU11 is a human monoclonal antibody that specifically binds to human IL-21R and can be potentially used in the treatment of arthritis and transplant rejection.
Figure 1 A depicts the result of an ELISA which shows that MU11 specifically bind to human IL-21 R.
Figure 2 The result of a binding assay analyzed by FACS which shows that both MUF and MU11 bind on the surface of human IL-21 R.
Figure 3 The result of an ELISA which shows that MUF inhibits the binding of human IL-21 to human IL-21 R.
Figure 4 The result of a cell-proliferation assay which shows that MU11 blocked the ability of IL-21 in COS cell culture media to increase the proliferation of mouse CD4+ T cells.
Figure 5 The result of a cell-proliferation assay which shows that MU11 blocked the ability of IL-21 in COS cell culture media to increase the proliferation of mouse CD8+ T cells, in a dose-dependent manner.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1347z | Mouse Anti-IL21R Recombinant Antibody (clone 44B3) | WB, IP, IF, ELISA | Mouse IgG2a, κ |
HPAB-0247CQ | Human Anti-IL21R Recombinant Antibody (clone 19F5) | Neut, WB, ELISA, FC, IHC | Human IgG1 |
FAMAB-1203CQ | Human Anti-IL21R Recombinant Antibody (clone ATR-107) | Inhib, FC, WB | Human IgG1 |
VS3-FY279 | Recombinant Mouse Anti-IL21R Antibody (clone 1C3B12) | ELISA, FC | Mouse IgG1 |
VS3-FY280 | Recombinant Mouse Anti-IL21R Antibody (clone 1C3G9) | ELISA, ICC, FC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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