Anti-Human NRG1 Recombinant Antibody (538.24) (CAT#: TAB-586MZ)
This anti-neuregulin 1 antibody can bind to both neuregulin-1α and neuregulin-1β isoforms. It can be potentially used in treating diseases or disorders, such as cancer.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Inhib
Figure 1 The inhibition of 125I-NRGβ1 binding to HER3-Fc by anti-NRG1 antibodies.
SPR
Figure 2 Binding affinities of 538.24 affinity matured variant anti-NRG1 IgGs for NRG1β as measured in a BIAcore assay.
SPR
Figure 3 Binding affinities of 538.24 affinity matured variant anti-NRG1 IgGs for NRG1α as measured in a BIAcore assay.
Specifications
- Immunogen
- Recombinant human NRGl-β ECD domain
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human antibody
- Specificity
- Human
- Clone
- 538.24
- Applications
- ELISA, Inhib, SPR
- Related Disease
- Head and neck squamous carcinoma (HNSCC), Lung cancer, Non- small cell lung cancer (NSCLC)
Applications
- Application Notes
- The antibody was validated for ELISA, Inhibition, Surface Plasmon Resonance. For details, refer to Published Data.
Target
- Alternative Names
- NRG1; neuregulin 1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2; pro-neuregulin-1, membrane-bound isoform; pro-NRG1; glial growth factor; neu differentiation factor; sensory and motor neuron derived factor; heregulin, alpha (45kD, ERBB2 p185-activator)
- Gene ID
- 3084
- UniProt ID
- A6MW56
Related Resources
ErbB Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-579MZ | Mouse Anti-NRG1 Recombinant Antibody (TAB-579MZ) | ELISA, FC, WB | Mouse IgG |
| TAB-579MZ-S(P) | Mouse Anti-NRG1 Recombinant Antibody; scFv Fragment (TAB-579MZ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-580MZ-S(P) | Mouse Anti-NRG1 Recombinant Antibody; scFv Fragment (TAB-580MZ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-581MZ-S(P) | Mouse Anti-NRG1 Recombinant Antibody; scFv Fragment (TAB-581MZ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-582MZ-S(P) | Mouse Anti-NRG1 Recombinant Antibody; scFv Fragment (TAB-582MZ-S(P)) | ELISA, FC | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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