Human Anti-NRG1 Recombinant Antibody (VS-0522-LC116) (CAT#: VS-0522-LC116)
This product is a human antibody that recognizes NRG1 protein of rat, human, mouse.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10964/1446_D11_3_selected.jpg
(Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10964/1446_D11_3_selected.jpg
Figure 2 IHC staining of human caudate
(Immunohistochemical staining of human caudate shows weak positivity.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10964/27907_B_8_7_selected.jpg
(Immunohistochemical staining of human caudate shows weak positivity.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10964/27907_B_8_7_selected.jpg
Figure 3 Cerebral cortex
(Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10964/27907_B_7_5.jpg
(Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10964/27907_B_7_5.jpg
Figure 4 Cerebellum
(Cells in granular layer Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in molecular layer Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Purkinje cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10964/27907_B_8_8.jpg
(Cells in granular layer Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in molecular layer Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Purkinje cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10964/27907_B_8_8.jpg
Figure 5 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10964/27907_A_7_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10964/27907_A_7_8.jpg
Figure 6 RNA cell line category: Cell line enhanced (A549, BJ, fHDF/TERT166, GAMG, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000157168-NRG1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000157168-NRG1
Specifications
- Immunogen
- The neuregulin-HBD antigen.
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Human NRG1
- Species Reactivity
- Rat, Human, Mouse
- Applications
- ICC, WB
- Conjugate
- Unconjugated
- Related Disease
- Schizophrenia 6 and Lung Cancer
Product Property
- Purification
- Protein A purified
- Format
- Liquid
- Concentration
- 1 mg/ml
- Buffer
- PBS
- Preservative
- 0.02% Proclin 300
- Storage
- Store at 4°C for short term. For long term storage, store at-20°C, avoiding freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Immunocytochemistry and Western Blot.
Target
- Alternative Names
- GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2; pro-neuregulin-1, membrane-bound isoform; acetylcholine receptor-inducing activity; glial growth factor 2; heregulin, alpha (45kD, ERBB2 p185-activator); neu differentiation factor; pro-NRG1; sensory and motor neuron derived factor
- Gene ID
- 3084
- UniProt ID
- Q02297
Related Resources
ErbB Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "NRG1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1480z | Mouse Anti-NRG1 Recombinant Antibody (clone 9G4) | WB, ELISA, IF | Mouse IgG1 |
| MOB-1459CT | Recombinant Mouse anti-Human NRG1 Monoclonal antibody (NN0594-2Z56) | WB | |
| VS-0522-LC114 | Mouse Anti-NRG1 Recombinant Antibody (VS-0522-LC114) | ICC, WB | Mouse IgG2a |
| VS-0522-LC115 | Rat Anti-NRG1 Recombinant Antibody (VS-0522-LC115) | ICC, WB | Rat IgG2b |
| VS-0723-WK111 | Rabbit Anti-NRG1 Recombinant Antibody (VS-0723-WK111) | ELISA, FC | Rabbit IgG |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-579MZ | Mouse Anti-NRG1 Recombinant Antibody (TAB-579MZ) | ELISA, FC, WB | Mouse IgG |
| TAB-580MZ | Mouse Anti-NRG1 Recombinant Antibody (TAB-580MZ) | ELISA, FC, WB | Mouse IgG |
| TAB-581MZ | Mouse Anti-NRG1 Recombinant Antibody (TAB-581MZ) | ELISA, FC, WB | Mouse IgG |
| TAB-582MZ | Mouse Anti-NRG1 Recombinant Antibody (TAB-582MZ) | ELISA, FC, WB | Mouse IgG |
| TAB-579MZ-S(P) | Mouse Anti-NRG1 Recombinant Antibody; scFv Fragment (TAB-579MZ-S(P)) | ELISA, FC | Mouse scFv |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-586MZ | Anti-Human NRG1 Recombinant Antibody (538.24) | ELISA, Inhib, SPR | Human antibody |
| TAB-587MZ | Anti-Human NRG1 Recombinant Antibody (538.24.71) | ELISA, Inhib, SPR, FuncS | Human antibody |
| TAB-588MZ | Anti-Human NRG1 Recombinant Antibody (526.9) | ELISA, Inhib | Human antibody |
| TAB-586MZ-S(P) | Anti-Human NRG1 Recombinant Antibody scFv Fragment (538.24) | ELISA | Human antibody |
| TAB-587MZ-S(P) | Anti-Human NRG1 Recombinant Antibody scFv Fragment (538.24.71) | ELISA | Human antibody |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-583MZ-S(P) | Mouse Anti-NRG1 Recombinant Antibody; scFv Fragment (TAB-583MZ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-584MZ-S(P) | Mouse Anti-NRG1 Recombinant Antibody; scFv Fragment (TAB-584MZ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-583MZ-F(E) | Human Anti-NRG1 Recombinant Antibody; Fab Fragment (TAB-583MZ-F(E)) | ELISA, FC | Chimeric (mouse/human) Fab |
| TAB-584MZ-F(E) | Human Anti-NRG1 Recombinant Antibody; Fab Fragment (TAB-584MZ-F(E)) | ELISA, FC | Chimeric (mouse/human) Fab |
| TAB-585MZ-F(E) | Human Anti-NRG1 Recombinant Antibody; Fab Fragment (TAB-585MZ-F(E)) | ELISA, FC | Chimeric (mouse/human) Fab |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4349 | Hi-Affi™ Recombinant Rabbit Anti-NRG1 Monoclonal Antibody (SI439DS) | ELISA | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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