Human Anti-RSPO3 Recombinant Antibody (clone h131R008) (CAT#: HPAB-0036CQ)

The antibody specifically bind human RSPO3 proteins and modulate β-catenin activity. The antibody inhibits β-catenin signaling.

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Inhib

Figure 1 Inhibition of tumor growth with anti-RSPO anti bodies.

LU25 NSCLC lung tumor cells were injected subcu taneously into NOD/SCID mice. Mice were treated with anti RSPO3 antibody 131R008 (-▲-), paclitaxel alone (-○-), a combination of anti-RSPO3 antibody 131R008 and paclitaxel (-●-), or a control antibody (-■-). Data is shown as tumor volume (mm) over days post-treatment.


Specifications

  • Host Species
  • Human
  • Derivation
  • Humanized
  • Type
  • Humanized IgG1, κ
  • Specificity
  • Human RSPO3
  • Species Reactivity
  • Human, Mouse
  • Clone
  • h131R008
  • Applications
  • ELISA, Inhib
  • Related Disease
  • Non-small cell lung tumor

Applications

  • Application Notes
  • This antibody has been tested for use in Inhibition. Please see the Published Data for further information.

Target

  • Alternative Names
  • RSPO3; R-spondin 3; PWTSR; THSD2; CRISTIN1; R-spondin-3; R-spondin 3 homolog; roof plate-specific spondin-3; protein with TSP type-1 repeat; thrombospondin, type I, domain containing 2; thrombospondin type-1 domain-containing protein 2

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

See other products for "RSPO3"

* Abbreviations
3D IHC3D Immunohistochemistry
ActivActivation
AgonistAgonist
ApopApoptosis
BABioassay
BIBioimaging
BlockBlocking
Cell ScreeningCell Screening
SeparationCell Separation
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
CostimCostimulation
CytCytotoxicity
DepletionDepletion
DBDot Blot
EMElectron Microscopy
ELISAEnzyme-linked Immunosorbent Assay
ELISPOTEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FuncSFunctional Assay
GSGel Super Shift Assay
HAHemagglutination
IAImmunoassay
IBImmunoblotting
ICCImmunocytochemistry
IDImmunodiffusion
IFImmunofluorescence
IHCImmunohistochemistry
IHC-FrImmunohistochemistry-Frozen
IHC-PImmunohistochemistry-Paraffin
REImmunohistology - Resin Sections
IPImmunoprecipitation
IRMAImmunoradiometric Assay
SHIn situ hybridization
InhibInhibition
ICFCIntracellular Staining for Flow Cytometry
KO/KD-WBKnockout/Knockdown target confirmation by Western Blot
Live cell imagingLive cell imaging
CyTOF®Mass Cytometry
MeDIPMethylated DNA Immunoprecipitation
MultiplexMultiplex bead-based assay
NeutNeutralization
PPProtein Purification
PGProteogenomics
RIRadial Immunodiffusion
RIARadioimmunoassay
StimStimulation
SPRSurface Plasmon Resonance
TCTissue Culture
TBTurbidimetry
WBWestern Blot

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