Anti-Human RTN4 Recombinant Antibody (11C7) (CAT#: TAB-531MZ)
This antibody 11C7 is capable of binding to the human NogoA polypeptide or human NiG or human NiG-D20 or human NogoA_623-640. Such a binding molecule can be potentially used in treatment studies of diseases associated with nerve repair.
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ICC
Figure 1 Immunocytochemistry of oligodendrocytes from P9 rat cerebellar cultures and hNogo-A-CHO cells with purified human anti Nogo antiserum.
Reticular staining pattern of fixed oligodendrocytes with monoclonal antibody 11C7
Reindl, M., Khantane, S., Ehling, R., Schanda, K., Lutterotti, A., Brinkhoff, C., ... & Bandtlow, C. E. (2003). Serum and cerebrospinal fluid antibodies to Nogo-A in patients with multiple sclerosis and acute neurological disorders. Journal of neuroimmunology, 145(1-2), 139-147.
ICC
Figure 2 Immunocytochemistry of oligodendrocytes from P9 rat cerebellar cultures and hNogo-A-CHO cells with purified human anti Nogo antiserum.
Reticular staining of CHO cells transiently expressing human Nogo-A with purified human monoclonal antibody 11C7 (green).
Reindl, M., Khantane, S., Ehling, R., Schanda, K., Lutterotti, A., Brinkhoff, C., ... & Bandtlow, C. E. (2003). Serum and cerebrospinal fluid antibodies to Nogo-A in patients with multiple sclerosis and acute neurological disorders. Journal of neuroimmunology, 145(1-2), 139-147.
Specifications
- Immunogen
- Synthetic NogoA peptides
- Host Species
- Mouse
- Specificity
- Human
- Clone
- 11C7
- Applications
- ELISA, ICC
- Related Disease
- Diseases associated with nerve repair
Applications
- Application Notes
- The antibody was validated for ELISA, Immunocytochemistry. For details, refer to Published Data.
Target
- Alternative Names
- RTN4; reticulon 4; ASY; NSP; NOGO; NOGOC; RTN-X; NOGO-A; NSP-CL; Nogo-B; Nogo-C; RTN4-A; RTN4-C; RTN4-B1; RTN4-B2; NI220/250; Nbla00271; Nbla10545; reticulon-4; foocen; Human NogoA; reticulon 5; My043 protein; neurite outgrowth inhibitor; neurite growth inhibitor 220; neuroendocrine-specific protein C homolog
- Gene ID
- 57142
- UniProt ID
- Q9NQC3
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-242 | Anti-Human RTN-4 Recombinant Antibody (Atinumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG4 - kappa |
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To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-531MZ, RRID: AB_3111970)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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