Anti-Human RTN-4 Recombinant Antibody (TAB-242) (CAT#: TAB-242)
Recombinant monoclonal antibody to RTN-4. It is an immunomodulator. It binds to reticulon 4.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/if_selected.jpg
Figure 2 IHC staining of human testis
(Immunohistochemical staining of human testis shows strong cytoplasmic positivity in seminiferous ducts cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/54863_A_4_6_selected.jpg
(Immunohistochemical staining of human testis shows strong cytoplasmic positivity in seminiferous ducts cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/54863_A_4_6_selected.jpg
Figure 3 IHC staining of human testis
(Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5388/13996_A_6_6_selected.jpg
(Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5388/13996_A_6_6_selected.jpg
Figure 4 Cerebral cortex
(Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/54863_B_8_5.jpg
(Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/54863_B_8_5.jpg
Figure 5 Cerebellum
(Cells in granular layer Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Cells in molecular layer Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Purkinje cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5388/13996_B_7_8.jpg
(Cells in granular layer Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Cells in molecular layer Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Purkinje cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5388/13996_B_7_8.jpg
Figure 6 Colon
(Enterocytes - Mucosal lymphoid cells Staining: Low Intensity: Moderate Quantity: <25% Peripheral nerve/ganglion Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/54863_A_9_3.jpg
(Enterocytes - Mucosal lymphoid cells Staining: Low Intensity: Moderate Quantity: <25% Peripheral nerve/ganglion Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/54863_A_9_3.jpg
Figure 7 Testis
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Round or early spermatids Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/54863_A_4_6.jpg
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Round or early spermatids Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/54863_A_4_6.jpg
Figure 8 RNA cell line category: Cell line enhanced (HHSteC)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115310-RTN4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115310-RTN4
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- IgG4 - kappa
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- Suitable for use in WB, Neut, ELISA, IF, IP, FuncS, FC and most other immunological methods.
- Related Disease
- Spinal cord injury, acute
Product Property
- Purity
- >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
- Storage
- Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Target
- Alternative Names
- Atinumab;1226761-65-4;ATI355;RTN4;reticulon 4;reticulon-4;ASY;KIAA0886;NOGO;NSP CL;foocen;Human NogoA;reticulon 5;My043 protein;neurite outgrowth inhibitor;neurite growth inhibitor 220;neuroendocrine-specific protein C homolog;NSP;NOGOC;RTN-X;NOGO-A;NSP-C
- Gene ID
- 57142
- UniProt ID
- Q9NQC3
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2437z | Mouse Anti-RTN4 Recombinant Antibody (clone 28B12) | WB, ELISA, IF, IP | Mouse IgM, κ |
| HPAB-0294CQ | Mouse Anti-RTN4 Recombinant Antibody (clone mAb 3A6) | ELISA, WB | Mouse IgG1 |
| HPAB-0295CQ | Human Anti-RTN4 Recombinant Antibody (clone h3A6) | ELISA, WB | Human IgG4 |
| HPAB-0047-WJ | Mouse Anti-RTN4 Recombinant Antibody (clone 6F2) | ELISA, WB, Inhib, IHC, IF | Mouse IgG |
| MRO-1101-CN | Recombinant Rabbit Anti-RTN4 Monoclonal Antibody (JM02-34) | WB, IF, IHC, IP, FC | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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