Anti-Human RTN-4 Recombinant Antibody (TAB-242)

Name: Anti-Human RTN-4 Recombinant Antibody (TAB-242)
SKU: TAB-242
Rating: 5 (1 reviews)

CAT#: TAB-242

Recombinant monoclonal antibody to RTN-4. It is an immunomodulator. It binds to reticulon 4.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/if_selected.jpg

Normal Tissue Figure 2 IHC staining of human testis

Immunohistochemical staining of human testis shows strong cytoplasmic positivity in seminiferous ducts cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/54863_A_4_6_selected.jpg

Normal Tissue Figure 3 IHC staining of human testis

Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5388/13996_A_6_6_selected.jpg

Normal Tissue Figure 4 Cerebral cortex

Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/54863_B_8_5.jpg

Normal Tissue Figure 5 Cerebellum

Cells in granular layer Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Cells in molecular layer Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Purkinje cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5388/13996_B_7_8.jpg

Normal Tissue Figure 6 Colon

Enterocytes - Mucosal lymphoid cells Staining: Low Intensity: Moderate Quantity: <25% Peripheral nerve/ganglion Staining: High Intensity: Strong

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/54863_A_9_3.jpg

Normal Tissue Figure 7 Testis

Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Round or early spermatids Staining: High Intensity: Strong Quantity:>75%

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/54863_A_4_6.jpg

RNA Expression Figure 8 RNA cell line category: Cell line enhanced (HHSteC)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115310-RTN4

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Specifications

Immunogen
The details of the immunogen for this antibody are not available.

Host Species
Human

Derivation
Human

Type
IgG4 - kappa

Specificity
Tested positive against native human antigen.

Species Reactivity
Human

Applications
Suitable for use in WB, Neut, ELISA, IF, IP, FuncS, FC and most other immunological methods.

Related Disease
Spinal cord injury, acute

Product Property

Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

Storage
Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

Target

Alternative Names
Atinumab;1226761-65-4;ATI355;RTN4;reticulon 4;reticulon-4;ASY;KIAA0886;NOGO;NSP CL;foocen;Human NogoA;reticulon 5;My043 protein;neurite outgrowth inhibitor;neurite growth inhibitor 220;neuroendocrine-specific protein C homolog;NSP;NOGOC;RTN-X;NOGO-A;NSP-C

Gene ID
57142

UniProt ID
Q9NQC3

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-242.pdf

MSDS

MSDS - TAB-242.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Protocol & Troubleshooting

Immunofluorescence (IF)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

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CAT	Product Name	Application	Type
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TAB-534MZ-S(P)	Human Anti-RTN4 Recombinant Antibody; scFv Fragment (TAB-534MZ-S(P))	ELISA, FC	Humanized scFv
TAB-535MZ-S(P)	Human Anti-RTN4 Recombinant Antibody; scFv Fragment (TAB-535MZ-S(P))	ELISA, FC	Humanized scFv
TAB-536MZ-S(P)	Human Anti-RTN4 Recombinant Antibody; scFv Fragment (TAB-536MZ-S(P))	ELISA, FC	Humanized scFv
TAB-537MZ-S(P)	Human Anti-RTN4 Recombinant Antibody; scFv Fragment (TAB-537MZ-S(P))	ELISA, FC	Humanized scFv

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TAB-531MZ	Anti-Human RTN4 Recombinant Antibody (11C7)	ELISA, ICC
TAB-532MZ	Mouse Anti-RTN4 Recombinant Antibody (TAB-532MZ)	ELISA, FC	Mouse IgG
TAB-531MZ-S(P)	Anti-Human RTN4 Recombinant Antibody scFv Fragment (11C7)	ELISA, ICC
TAB-532MZ-S(P)	Mouse Anti-RTN4 Recombinant Antibody; scFv Fragment (TAB-532MZ-S(P))	ELISA, FC	Mouse scFv
TAB-531MZ-F(E)	Anti-Human RTN4 Recombinant Antibody Fab Fragment (11C7)	ELISA, ICC

CAT	Product Name	Application	Type
TAB-533MZ	Human Anti-RTN4 Recombinant Antibody (TAB-533MZ)	ELISA, FC	Chimeric (mouse/human) IgG
TAB-533MZ-S(P)	Mouse Anti-RTN4 Recombinant Antibody; scFv Fragment (TAB-533MZ-S(P))	ELISA, FC	Mouse scFv
TAB-533MZ-F(E)	Human Anti-RTN4 Recombinant Antibody; Fab Fragment (TAB-533MZ-F(E))	ELISA, FC	Chimeric (mouse/human) Fab

CAT	Product Name	Application	Type
MOR-3139	Hi-Affi™ Recombinant Rabbit Anti-RTN4 Monoclonal Antibody (DS3139AB)	WB, FC	IgG

CAT	Product Name	Application	Type
HPAB-0294CQ-F(E)	Mouse Anti-RTN4 Recombinant Antibody (clone mAb 3A6); Fab Fragment	ELISA, WB	Mouse Fab
HPAB-0295CQ-F(E)	Human Anti-RTN4 Recombinant Antibody (clone h3A6); Fab Fragment	ELISA, WB	Human Fab
HPAB-0047-WJ-F(E)	Mouse Anti-RTN4 Recombinant Antibody (clone 6F2); Fab Fragment	ELISA, WB	Mouse Fab
HPAB-0901-FY-S(P)	Human Anti-RTN4 Recombinant Antibody; scFv Fragment (HPAB-0901-FY-S(P))	ELISA, Neut	Humanized scFv

CAT	Product Name	Application	Type
HPAB-0294CQ-S(P)	Mouse Anti-RTN4 Recombinant Antibody (clone mAb 3A6); scFv Fragment	ELISA, WB	Mouse scFv
HPAB-0295CQ-S(P)	Human Anti-RTN4 Recombinant Antibody (clone h3A6); scFv Fragment	ELISA, WB	Human scFv
HPAB-0047-WJ-S(P)	Mouse Anti-RTN4 Recombinant Antibody (clone 6F2); scFv Fragment	ELISA, WB	Mouse scFv
HPAB-0901-FY-F(E)	Human Anti-RTN4 Recombinant Antibody; Fab Fragment (HPAB-0901-FY-F(E))	ELISA, Neut	Humanized Fab

CAT	Product Name	Application	Type
AFC-TAB-903	Afuco™ Anti-RTN4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-903)	IF, IP, Neut, FuncS, ELISA, FC	ADCC enhanced antibody
AFC-TAB-242	Afuco™ Anti-RTN4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-242)	ELISA, FC, IP, FuncS, IF, Neut	ADCC enhanced antibody

CAT	Product Name	Application	Type
VS-0425-FY158	Mouse Anti-RTN4 (clone 11C7) scFv-Fc Chimera	ELISA, ICC	Mouse IgG1, scFv-Fc

CAT	Product Name	Application	Type
VS-0425-YC538	Recombinant Anti-RTN4 Vesicular Antibody, EV Displayed (VS-0425-YC538)	ELISA, FC, Neut, Cell-uptake

CAT	Product Name	Application
VS-0525-XY6264	Anti-RTN4 Immunohistochemistry Kit	IHC
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