Mouse Anti-RTN4 Recombinant Antibody (clone 6F2); Fab Fragment

Name: Mouse Anti-RTN4 Recombinant Antibody (clone 6F2); Fab Fragment
SKU: HPAB-0047-WJ-F(E)
Rating: 5 (1 reviews)

CAT#: HPAB-0047-WJ-F(E)

This product is a mouse monoclonal antibody targeting reticulon 4B (RTN4B). This antibody inhibits the growth of cancer cells and is expected for clinical anti-cancer therapy.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/if_selected.jpg

Normal Tissue Figure 2 IHC staining of human testis

Immunohistochemical staining of human testis shows strong cytoplasmic positivity in seminiferous ducts cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/54863_A_4_6_selected.jpg

Normal Tissue Figure 3 IHC staining of human testis

Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5388/13996_A_6_6_selected.jpg

Normal Tissue Figure 4 Cerebral cortex

Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/54863_B_8_5.jpg

Normal Tissue Figure 5 Cerebellum

Cells in granular layer Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Cells in molecular layer Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Purkinje cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5388/13996_B_7_8.jpg

Normal Tissue Figure 6 Colon

Enterocytes - Mucosal lymphoid cells Staining: Low Intensity: Moderate Quantity: <25% Peripheral nerve/ganglion Staining: High Intensity: Strong

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/54863_A_9_3.jpg

Normal Tissue Figure 7 Testis

Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Round or early spermatids Staining: High Intensity: Strong Quantity:>75%

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/54863_A_4_6.jpg

RNA Expression Figure 8 RNA cell line category: Cell line enhanced (HHSteC)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115310-RTN4

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Specifications

Immunogen
Polypeptide RTN4B

Host Species
Mouse

Type
Mouse Fab

Specificity
Human RTN4B

Species Reactivity
Human

Clone
6F2

Applications
ELISA, WB

Related Disease
Lung cancer

Product Property

Purity
>95% as determined by SDS-PAGE and HPLC analysis

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
RTN4; RTN4-B1; RTN4-A; KIAA0886; Nogo-B; NOGOC; Neuroendocrine-Specific Protein; NI220/250; NOGO; Nbla00271; RTN-X; Nogo-C; Nbla10545; Neurite Growth Inhibitor 220; NSP; Nogo Protein; Neurite Outgrowth Inhibitor; Human NogoA; Foocen; ASY

Gene ID
57142

UniProt ID
Q9NQC3

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - HPAB-0047-WJ-F(E).pdf

MSDS

MSDS - HPAB-0047-WJ-F(E).pdf

COA

Certificate of Analysis Lookup

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CAT
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