Recombinant Mouse Anti-SELPLG Antibody (KPL-1) (CAT#: NEUT-1937CQ)
This antibody is a mouse monoclonal antibody that binds specifically to CD162, and it can neutralize the bioactivity of CD162.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HEL
(Immunofluorescent staining of human cell line HEL shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11256/1847_F9_37_cr5abb5d8e30c09_selected.jpg
(Immunofluorescent staining of human cell line HEL shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11256/1847_F9_37_cr5abb5d8e30c09_selected.jpg
Figure 2 High expression in spleen.
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2431/6181_B_8_4_val_selected.jpg
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2431/6181_B_8_4_val_selected.jpg
Figure 3 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69062/170043_A_9_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69062/170043_A_9_5.jpg
Figure 4 Lymph node
(Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69062/170043_A_9_8.jpg
(Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69062/170043_A_9_8.jpg
Figure 5 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, JURKAT, Karpas-707, RPMI-8226, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000110876-SELPLG
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000110876-SELPLG
Specifications
- Host Species
- Mouse
- Type
- IgG1, κ
- Specificity
- The antibody epitope was mapped to a site within a consensus tyrosine sulfation motif of CD162, previously shown to be essential for interaction with P selectin (and now shown to be essential for recognition of CD162 by L selectin).
- Species Reactivity
- Human
- Clone
- KPL-1
- Applications
- Used for immunoassay techniques such as: Blocking; Western Blot; Immunoprecipitation; Immunohistochemistry-Paraffin; Immunohistochemistry-Frozen; Flow Cytometry
- Conjugate
- Unconjugated
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze-thaw cycles.
Target
- Alternative Names
- SELPLG; selectin P ligand; CLA; CD162; PSGL1; PSGL-1; P-selectin glycoprotein ligand 1; cutaneous lymphocyte-associated associated antigen
- Gene ID
- 6404
- UniProt ID
- Q14242
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Flow Cytometry (FC) related Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-555CL | Human Anti-SELPLG Recombinant Antibody (TAB-555CL) | ELISA | Human IgG |
Customer Reviews and Q&As
Customer Review
Q&As
Excellent Specificity
This antibody has shown remarkable specificity in detecting human SELPLG. In my studies on cell adhesion molecules, accurate detection is crucial. The Anti-SELPLG Antibody (CABT-L2448) delivered clear signals without non-specific binding. It enhanced the reliability of my data on leukocyte trafficking. The product was easy to use, and the detailed datasheet provided useful guidance. I am very satisfied with its performance.
Great Value
Considering its high performance, the Anti-SELPLG Antibody (CABT-L2448) offers great value for money. Our lab operates on a tight budget, and finding cost-effective yet reliable reagents is essential. This antibody met all our requirements without compromising on quality. It has helped advance our studies on vascular biology and leukocyte-endothelial interactions. I would definitely repurchase this product.
Valuable Research Tool
The Anti-SELPLG Antibody (CABT-L2448) has become an invaluable tool in our lab. We're investigating the role of SELPLG in autoimmune diseases, and this antibody has enabled us to detect subtle changes in SELPLG expression. The quality and consistency have been outstanding, contributing significantly to the progress of our research. I appreciate the excellent customer support provided by Creative Biolabs as well.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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