Recombinant Mouse Anti-SELPLG Antibody (KPL-1)
CAT#: NEUT-1937CQ
This antibody is a mouse monoclonal antibody that binds specifically to CD162, and it can neutralize the bioactivity of CD162.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11256/1847_F9_37_cr5abb5d8e30c09_selected.jpg
Normal Tissue
Figure 2 High expression in spleen.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2431/6181_B_8_4_val_selected.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69062/170043_A_9_5.jpg
Normal Tissue
Figure 4 Lymph node
Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69062/170043_A_9_8.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, JURKAT, Karpas-707, RPMI-8226, U-266/70, U-266/84)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000110876-SELPLG
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Specifications
- Host Species
- Mouse
- Type
- IgG1, κ
- Specificity
- The antibody epitope was mapped to a site within a consensus tyrosine sulfation motif of CD162, previously shown to be essential for interaction with P selectin (and now shown to be essential for recognition of CD162 by L selectin).
- Species Reactivity
- Human
- Clone
- KPL-1
- Applications
- Used for immunoassay techniques such as: Blocking; Western Blot; Immunoprecipitation; Immunohistochemistry-Paraffin; Immunohistochemistry-Frozen; Flow Cytometry
- Conjugate
- Unconjugated
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze-thaw cycles.
Target
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Excellent Specificity
This antibody has shown remarkable specificity in detecting human SELPLG. In my studies on cell adhesion molecules, accurate detection is crucial. The Anti-SELPLG Antibody (CABT-L2448) delivered clear signals without non-specific binding. It enhanced the reliability of my data on leukocyte trafficking. The product was easy to use, and the detailed datasheet provided useful guidance. I am very satisfied with its performance.
Great Value
Considering its high performance, the Anti-SELPLG Antibody (CABT-L2448) offers great value for money. Our lab operates on a tight budget, and finding cost-effective yet reliable reagents is essential. This antibody met all our requirements without compromising on quality. It has helped advance our studies on vascular biology and leukocyte-endothelial interactions. I would definitely repurchase this product.
Valuable Research Tool
The Anti-SELPLG Antibody (CABT-L2448) has become an invaluable tool in our lab. We're investigating the role of SELPLG in autoimmune diseases, and this antibody has enabled us to detect subtle changes in SELPLG expression. The quality and consistency have been outstanding, contributing significantly to the progress of our research. I appreciate the excellent customer support provided by Creative Biolabs as well.
Q&As
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What are the main applications of the Anti-SELPLG Antibody (Catalog No. CABT-L2448) in laboratory research?
A: The Anti-SELPLG Antibody (CABT-L2448) is primarily used in Enzyme-Linked Immunosorbent Assays (ELISA) to detect and quantify SELPLG protein levels in various human samples. SELPLG, also known as P-selectin glycoprotein ligand-1 (PSGL-1), plays a significant role in leukocyte trafficking and cell adhesion. This antibody helps researchers study immune responses, inflammation processes, and related diseases by providing accurate measurement of SELPLG expression.
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Is this Anti-SELPLG Antibody suitable for detecting SELPLG in non-human samples?
A: The Anti-SELPLG Antibody (CABT-L2448) is a mouse monoclonal antibody specifically designed to target human SELPLG. Its reactivity with non-human species has not been validated, so it may not provide reliable results in samples from other species. Researchers working with non-human models should consider antibodies validated for their specific species to ensure accuracy and specificity.
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What role does SELPLG play in disease research, and how can this antibody assist?
A: SELPLG is involved in mediating leukocyte rolling and adhesion during inflammation, making it a critical molecule in the study of immune responses and inflammatory diseases. By using the Anti-SELPLG Antibody (CABT-L2448), researchers can accurately measure SELPLG expression levels in various conditions, aiding in the understanding of diseases such as autoimmune disorders, cardiovascular diseases, and other inflammatory conditions.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "SELPLG"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1675z | Mouse Anti-SELPLG Recombinant Antibody (clone 28C8) | FC, ICC, IF, IHC | Mouse IgG1 |
| HPAB-0598-CN | Human Anti-SELPLG Recombinant Antibody (HPAB-0598-CN) | ELISA, FC | Humanized IgG4, κ |
| HPAB-0597-CN | Human Anti-SELPLG Recombinant Antibody (HPAB-0597-CN) | ELISA, FC | Chimeric (mouse/human) IgG1 |
| HPAB-0101-LS | Mouse Anti-SELPLG Recombinant Antibody (HPAB-0101-LS) | ELISA | Mouse IgG1 |
| MOB-259YJL | Rabbit Anti-SELPLG Recombinant Antibody (clone CBS244), PE | FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-555CL | Human Anti-SELPLG Recombinant Antibody (TAB-555CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-265CT | Anti-Human P-selectin glycoprotein ligand 1 (PSGL-1) Recombinant Antibody | WB, ELISA | Human antibody |
| TAB-265CT-S(P) | Anti-Human P-selectin glycoprotein ligand 1 (PSGL-1) Recombinant Antibody scFv Fragment | WB, ELISA | Human antibody |
| TAB-269CT-S(P) | Anti-Human P-selectin glycoprotein ligand 1 (PSGL-1) Recombinant Antibody scFv Fragment (PSG3) | ELISA, FC | Human antibody |
| TAB-270CT-S(P) | Anti-Human P-selectin glycoprotein ligand 1 (PSGL-1) Recombinant Antibody scFv Fragment (PSG5) | ELISA, FC | Human antibody |
| TAB-271CT-S(P) | Anti-Human P-selectin glycoprotein ligand 1 (PSGL-1) Recombinant Antibody scFv Fragment (PSG6) | ELISA, FC | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1938CQ | Recombinant Mouse Anti-SELPLG Antibody (3E2.25.5) | BL, FC, IHC, IHC-Fr, IHC-P, WB | IgG1 |
| NEUT-1939CQ | Recombinant Rat Anti-Selplg Antibody (4RA10) | BL, IHC | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1940CQ | Recombinant Mouse Anti-SELPLG Antibody (CHO131) | BL, CyTOF, FC | IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3204 | Hi-Affi™ Recombinant Rabbit Anti-SELPLG Monoclonal Antibody (DS3204AB) | WB, IP, IHC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0598-CN-S(P) | Human Anti-SELPLG Recombinant Antibody; scFv Fragment (HPAB-0598-CN-S(P)) | ELISA, FC | Humanized scFv |
| HPAB-0597-CN-S(P) | Mouse Anti-SELPLG Recombinant Antibody; scFv Fragment (HPAB-0597-CN-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0101-LS-S(P) | Mouse Anti-SELPLG Recombinant Antibody; scFv Fragment (HPAB-0101-LS-S(P)) | ELISA | Mouse scFv |
| HPAB-0102-LS-S(P) | Mouse Anti-SELPLG Recombinant Antibody; scFv Fragment (HPAB-0102-LS-S(P)) | ELISA | Mouse scFv |
| HPAB-0103-LS-S(P) | Mouse Anti-SELPLG Recombinant Antibody; scFv Fragment (HPAB-0103-LS-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0598-CN-F(E) | Human Anti-SELPLG Recombinant Antibody; Fab Fragment (HPAB-0598-CN-F(E)) | ELISA, FC | Humanized Fab |
| HPAB-0597-CN-F(E) | Human Anti-SELPLG Recombinant Antibody; Fab Fragment (HPAB-0597-CN-F(E)) | ELISA, FC | Human Fab |
| HPAB-0101-LS-F(E) | Mouse Anti-SELPLG Recombinant Antibody; Fab Fragment (HPAB-0101-LS-F(E)) | ELISA | Mouse Fab |
| HPAB-0102-LS-F(E) | Mouse Anti-SELPLG Recombinant Antibody; Fab Fragment (HPAB-0102-LS-F(E)) | ELISA | Mouse Fab |
| HPAB-0911-FY-S(P) | Mouse Anti-SELPLG Recombinant Antibody (clone M-DC8); Fab Fragment | FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY195 | CytoStream™ Rat Anti-SELPLG Recombinant Antibody (VS-0225-XY195) | FC | Rat IgG1, kappa |
| VS-0225-XY196 | CytoStream™ Rat Anti-SELPLG Recombinant Antibody (clone 4RA10) | FC, Block, IP, WB | Rat IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC186 | Recombinant Anti-SELPLG Vesicular Antibody, EV Displayed (VS-0425-YC186) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6439 | Anti-SELPLG Immunohistochemistry Kit | IHC | |
| VS-0525-XY6440 | Anti-Mouse SELPLG Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC162 | Recombinant Anti-SELPLG (AA 50-60 x AA 119-319) Biparatopic Antibody, Tandem scFv | ELISA | Tandem scFv |
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