Recombinant Anti-SELPLG (AA 50-60 x AA 119-319) Biparatopic Antibody, Tandem scFv (CAT#: VS-0525-YC162)
This biparatopic antibody (bpAb) binds two distinct epitopes on SELPLG (selectin P ligand). Its tandem scFv arms were designed for simultaneous, high-affinity binding to amino acids 50-60 and 119-319 of the SELPLG protein.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HEL
(Immunofluorescent staining of human cell line HEL shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11256/1847_F9_37_cr5abb5d8e30c09_selected.jpg
(Immunofluorescent staining of human cell line HEL shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11256/1847_F9_37_cr5abb5d8e30c09_selected.jpg
Figure 2 High expression in spleen.
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2431/6181_B_8_4_val_selected.jpg
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2431/6181_B_8_4_val_selected.jpg
Figure 3 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69062/170043_A_9_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69062/170043_A_9_5.jpg
Figure 4 Lymph node
(Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69062/170043_A_9_8.jpg
(Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69062/170043_A_9_8.jpg
Figure 5 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, JURKAT, Karpas-707, RPMI-8226, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000110876-SELPLG
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000110876-SELPLG
Specifications
- Host Animal 1
- Mouse
- Host Animal 2
- Mouse
- Specificity
- Human SELPLG
- Species Reactivity
- Human
- Type
- Tandem scFv
- Valency
- 1 + 1
- Epitope 1
- aa 50-60
- Epitope 2
- aa 119-319
- Purity
- >90%
- Purification
- Affinity purified
- Applications
- ELISA
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
- Long Name
- Selectin P Ligand
Target
- Introduction
- The antibody can induce apoptosis upon binding to P-Selectin Glycoprotein Ligand-1 (SELPLG) on activated T cells.
- Alternative Names
- CLA; CD162; PSGL1; PSGL-1
- Gene ID
- 6404
- UniProt ID
- Q14242
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1675z | Mouse Anti-SELPLG Recombinant Antibody (clone 28C8) | FC, ICC, IF, IHC | Mouse IgG1 |
| MOB-0454CT | Recombinant Mouse anti-Human SELPLG Monoclonal antibody (LQM-2) | BL, FC, IHC-Fr, IHC-P, IP, WB | |
| FN-058CQ | Recombinant Mouse Anti-SELPLG Antibody (PL1) | FC, Block, WB | Mouse IgG1 |
| MOB-259YJL | Rabbit Anti-SELPLG Recombinant Antibody (clone CBS244), PE | FC | Rabbit IgG |
| VS3-XY3498 | Rabbit Anti-SELPLG Recombinant Antibody (clone R03-8N8) | WB, IHC-P, ICC, IF, IP | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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