Recombinant Anti-SELPLG (AA 50-60 x AA 119-319) Biparatopic Antibody, Tandem scFv

CAT#: VS-0525-YC162

This biparatopic antibody (bpAb) binds two distinct epitopes on SELPLG (selectin P ligand). Its tandem scFv arms were designed for simultaneous, high-affinity binding to amino acids 50-60 and 119-319 of the SELPLG protein.

Gene Expression
Figure 1 IF staining of human cell line HEL Figure 2 High expression in spleen. Figure 3 Kidney Figure 4 Lymph node Figure 5 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, JURKAT, Karpas-707, RPMI-8226, U-266/70, U-266/84)

Specifications

  • Host Animal 1
  • Mouse
  • Host Animal 2
  • Mouse
  • Specificity
  • Human SELPLG
  • Species Reactivity
  • Human
  • Type
  • Tandem scFv
  • Valency
  • 1 + 1
  • Epitope 1
  • aa 50-60
  • Epitope 2
  • aa 119-319
  • Purity
  • >90%
  • Purification
  • Affinity purified
  • Applications
  • ELISA
  • Concentration
  • Lot specific
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
  • Long Name
  • Selectin P Ligand

Target

  • Introduction
  • The antibody can induce apoptosis upon binding to P-Selectin Glycoprotein Ligand-1 (SELPLG) on activated T cells.
  • Alternative Names
  • CLA; CD162; PSGL1; PSGL-1
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