Anti-Human SPP1 Recombinant Antibody Fab Fragment (MOR-6993) (CAT#: TAB-0848CL-F(E))
This human antibody can bind to osteopontin with high affinity and can neutralize both human and mouse osteopontin. It also may provide a method for treating various cancers.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line RPTEC TERT1
(Immunofluorescent staining of human cell line RPTEC TERT1 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27540/1789_G12_1_cr59549927dd49e_selected.jpg
(Immunofluorescent staining of human cell line RPTEC TERT1 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27540/1789_G12_1_cr59549927dd49e_selected.jpg
Figure 2 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/1763_H3_6_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/1763_H3_6_selected.jpg
Figure 3 Kidney
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/64396_A_7_5_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/64396_A_7_5_val_selected.jpg
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/64396_A_8_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/64396_A_8_3.jpg
Figure 5 Gallbladder
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/64396_A_6_4.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/64396_A_6_4.jpg
Figure 6 Lymph node
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/64396_A_9_8.jpg
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/64396_A_9_8.jpg
Figure 7 RNA cell line category: Cell line enhanced (EFO-21, Hep G2, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000118785-SPP1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000118785-SPP1
Specifications
- Host Species
- Human
- Derivation
- Phagemid library
- Type
- Human antibody
- Specificity
- Human
- Clone
- MOR-6993
- Applications
- ELISA
- Related Disease
- Breast cancer
Target
- Alternative Names
- SPP1; secreted phosphoprotein 1; OPN; BNSP; BSPI; ETA-1; osteopontin; uropontin; nephropontin; SPP1/CALPHA1 fusion; urinary stone protein; early T-lymphocyte activation 1; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1)
- Gene ID
- 6696
- UniProt ID
- A0A024RDE6
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibodies
Mouse Antibodies
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ScFv Antibodies
Fab Antibodies
ScFv-Fc Chimeras
IHC Kits & Antibodies
Biparatopic Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1403z | Mouse Anti-SPP1 Recombinant Antibody (clone 23F4) | ELISA, ICC, IF, IHC, WB | Mouse IgG1 |
| HPAB-0068-YC | Human Anti-SPP1 Recombinant Antibody (clone h2K1) | FuncS | Humanized IgG |
| HPAB-0069-YC | Human Anti-SPP1 Recombinant Antibody (clone c2K1) | FuncS | Chimeric (mouse/human) IgG, κ |
| HPAB-0070-YC | Human Anti-SPP1 Recombinant Antibody (clone R2K1v1.7) | ELISA | Humanized IgG |
| ZG-0075U | Rabbit Anti-SPP1 Recombinant Antibody (clone 10A1) | ELISA, WB, IHC | Rabbit IgG |
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