Mouse Anti-SPP1 (clone 23C3) scFv-Fc Chimera
CAT#: VS-0325-FY193
The anti-OPN scFv-Fc antibody targets Osteopontin (OPN), a multifunctional protein involved in bone remodeling, immune response, and cancer progression. This antibody provides specific targeting of OPN, with potential applications in research related to its role in inflammation, cancer biology, and therapeutic targeting.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RPTEC TERT1
Immunofluorescent staining of human cell line RPTEC TERT1 shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27540/1789_G12_1_cr59549927dd49e_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line Hep G2
Immunofluorescent staining of human cell line Hep G2 shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/1763_H3_6_selected.jpg
Normal Tissue
Figure 3 Kidney
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/64396_A_7_5_val_selected.jpg
Normal Tissue
Figure 4 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/64396_A_8_3.jpg
Normal Tissue
Figure 5 Gallbladder
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/64396_A_6_4.jpg
Normal Tissue
Figure 6 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/64396_A_9_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (EFO-21, Hep G2, RPTEC TERT1)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000118785-SPP1
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Specifications
- Immunogen
- Human Osteopontin
- Host Species
- Mouse
- Type
- Mouse IgG1, scFv-Fc
- Specificity
- Human SPP1
- Species Reactivity
- Human
- Clone
- 23C3
- Applications
- ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Secreted Phosphoprotein 1; Early T-Lymphocyte Activation 1; Urinary Stone Protein; Nephropontin; Osteopontin; Uropontin; BNSP; OPN; Secreted Phosphoprotein 1 (Osteopontin, Bone Sialoprotein I, Early T-Lymphocyte Activation 1)
- Gene ID
- 6696
- UniProt ID
- P10451
- Long Name
- Secreted Phosphoprotein 1
- Function
- Human SPP1 (Secreted phosphoprotein 1), also known as osteopontin, is a multifunctional protein involved in cell adhesion, migration, and signaling. It plays a role in bone remodeling, immune responses, and tumor progression.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
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| TAB-0846CL | Anti-Human SPP1 Recombinant Antibody (MOR-6990) | ELISA, Neut | Human antibody |
| TAB-0847CL | Anti-Human SPP1 Recombinant Antibody (MOR-6991) | ELISA | Human antibody |
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| TAB-0846CL-S(P) | Anti-Human SPP1 Recombinant Antibody scFv Fragment (MOR-6990) | ELISA | Human antibody |
| TAB-0847CL-S(P) | Anti-Human SPP1 Recombinant Antibody scFv Fragment (MOR-6991) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
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| BRD-0814MZ | Chicken Anti-Osteopontin Polyclonal IgY | ELISA, IHC, WB | Chicken antibody |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0068-YC | Human Anti-SPP1 Recombinant Antibody (clone h2K1) | FuncS | Humanized IgG |
| HPAB-0069-YC | Human Anti-SPP1 Recombinant Antibody (clone c2K1) | FuncS | Chimeric (mouse/human) IgG, κ |
| HPAB-0070-YC | Human Anti-SPP1 Recombinant Antibody (clone R2K1v1.7) | ELISA | Humanized IgG |
| FAMAB-1252CQ | Human Anti-SPP1 Recombinant Antibody (clone hu1A12) | WB, IF, ELISA, Inhib, Cyt | Human IgG1 |
| ZG-0075U | Rabbit Anti-SPP1 Recombinant Antibody (clone 10A1) | ELISA, WB, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0068-YC-S(P) | Human Anti-SPP1 Recombinant Antibody (clone h2K1); scFv Fragment | FuncS | Humanized scFv |
| HPAB-1079WJ-S(P) | Human Anti-SPP1 Recombinant Antibody (clone MOR-6990); scFv Fragment | ELISA | Human scFv |
| HPAB-1080WJ-S(P) | Human Anti-SPP1 Recombinant Antibody (clone MOR-6991); scFv Fragment | ELISA | Human scFv |
| HPAB-1081WJ-S(P) | Human Anti-SPP1 Recombinant Antibody (clone MOR-6993); scFv Fragment | ELISA | Human scFv |
| HPAB-0569-YJ-S(P) | Human Anti-SPP1 Recombinant Antibody (clone OPN-3); scFv Fragment | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0068-YC-F(E) | Human Anti-SPP1 Recombinant Antibody (clone h2K1); Fab Fragment | FuncS | Humanized Fab |
| HPAB-0069-YC-F(E) | Human Anti-SPP1 Recombinant Antibody (clone c2K1); Fab Fragment | FuncS | Human Fab |
| HPAB-0070-YC-F(E) | Human Anti-SPP1 Recombinant Antibody (clone R2K1v1.7); Fab Fragment | ELISA | Humanized Fab |
| HPAB-1363-FY-S(P) | Mouse Anti-SPP1 Recombinant Antibody (clone 1A12); Fab Fragment | WB, ELISA | Mouse Fab |
| HPAB-0569-YJ-F(E) | Human Anti-SPP1 Recombinant Antibody (clone OPN-3); Fab Fragment | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6866 | Anti-SPP1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6867 | Anti-Mouse SPP1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
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