Anti-Human SPP1 Recombinant Antibody scFv Fragment (MOR-6990) (CAT#: TAB-0846CL-S(P))
This human antibody scFv Fragment can bind to osteopontin with high affinity and can neutralize both human and mouse osteopontin. It also may provide a method for treating various cancers.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line RPTEC TERT1
(Immunofluorescent staining of human cell line RPTEC TERT1 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27540/1789_G12_1_cr59549927dd49e_selected.jpg
(Immunofluorescent staining of human cell line RPTEC TERT1 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27540/1789_G12_1_cr59549927dd49e_selected.jpg
Figure 2 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/1763_H3_6_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/1763_H3_6_selected.jpg
Figure 3 Kidney
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/64396_A_7_5_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/64396_A_7_5_val_selected.jpg
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/64396_A_8_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/64396_A_8_3.jpg
Figure 5 Gallbladder
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/64396_A_6_4.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/64396_A_6_4.jpg
Figure 6 Lymph node
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/64396_A_9_8.jpg
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27541/64396_A_9_8.jpg
Figure 7 RNA cell line category: Cell line enhanced (EFO-21, Hep G2, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000118785-SPP1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000118785-SPP1
Specifications
- Host Species
- Human
- Derivation
- Phagemid library
- Type
- Human antibody
- Specificity
- Human
- Clone
- MOR-6990
- Applications
- ELISA
- Related Disease
- Breast cancer
Target
- Alternative Names
- SPP1; secreted phosphoprotein 1; OPN; BNSP; BSPI; ETA-1; osteopontin; uropontin; nephropontin; SPP1/CALPHA1 fusion; urinary stone protein; early T-lymphocyte activation 1; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1)
- Gene ID
- 6696
- UniProt ID
- A0A024RDE6
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0843CL | Anti-Human SPP1 Recombinant Antibody (2K1) | sELISA | |
| TAB-0844CL | Anti-Human SPP1 Recombinant Antibody (4C1) | sELISA | |
| TAB-0849CL | Anti-Human SPP1 Recombinant Antibody (2G2) | WB | |
| TAB-0850CL | Anti-Human SPP1 Recombinant Antibody (2H2) | ELISA, FC | |
| TAB-0843CL-S(P) | Anti-Human SPP1 Recombinant Antibody scFv Fragment (2K1) | sELISA |
Customer Reviews and Q&As
Customer Review
Q&As
Remarkable Specificity and Application
This SPP1 Antibody scFv Fragment has transformed our cancer research studies. Its specificity for osteopontin has led to groundbreaking insights into breast cancer metastasis. The robust results in ELISA have enhanced our experimental accuracy.
Reliable in Cancer Research
Utilizing this antibody in our lab, we found consistent performance and reliable specificity toward osteopontin. It's become integral to our studies on tumor growth, backed by excellent technical support from Creative Biolabs.
Excellent for Long-Term Projects
Its sustained supply and batch consistency have ensured continuity in our multi-phase research. The reliable binding to SPP1 makes it indispensable for our in-depth cancer studies.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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